Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | KHK | P50053 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.39 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.39 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL27808517 | 0.84 | HDAC6 (0.50) | KHKMAPTRAB9AHDAC4HDAC6 | |
| Tert-Butyl Formate SCHEMBL27786378 | 0.82 | HRH3 (0.55) | GPR119MAPT | |
| Tert-Butyl Formate SCHEMBL27808400 | 0.81 | GCG (0.46) | KHKMAPTRAB9AHDAC4HDAC6 | |
| Tert-Butyl Formate SCHEMBL28787428 | 0.79 | KHK (0.63) | KHKHDAC4HDAC6JAK2BRD4 | |
| Tert-Butyl Formate SCHEMBL28822382 | 0.79 | MEN1 (0.47) | RAB9AHDAC4HDAC6SMYD3 | |
| SCHEMBL3638282 | 0.78 | GPR119 (0.69) | GPR119HDAC4HDAC6PRKAB2PRKAG1 | |
| Tert-Butyl Formate SCHEMBL28784361 | 0.75 | HRH3 (0.55) | GPR119 | |
| Tert-Butyl Formate SCHEMBL27759534 | 0.75 | HDAC4 (0.46) | HDAC4HDAC6DGAT2 | |
| Tert-Butyl Formate SCHEMBL27759535 | 0.75 | HDAC4 (0.46) | HDAC4HDAC6DGAT2 | |
| SCHEMBL3668182 | 0.74 | GPR119 (0.64) | GPR119HDAC4HDAC6DGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101778838-A | Azacyclylbenzamide derivatives as histamine-3 antagonists | WYETH CORP | 2010-07-14 | — | — | CN | disclosed |