Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3636321 | 0.90 | HRH3 (0.65) | HRH3KCNH2GPR119SMN1; SMN2MGLL | |
| Tert-Butyl Formate SCHEMBL28784361 | 0.89 | HRH3 (0.55) | HRH3KCNH2GPR119PTK2CACNA2D1 | |
| Hydrochloric Acid SCHEMBL3639931 | 0.89 | HRH3 (0.64) | HRH3KCNH2GPR119SMN1; SMN2MGLL | |
| SCHEMBL3665742 | 0.84 | HRH3 (0.62) | HRH3KCNH2GPR119MGLLKMT2A | |
| SCHEMBL3665747 | 0.84 | HRH3 (0.62) | HRH3KCNH2GPR119MGLLKMT2A | |
| Tert-Butyl Formate SCHEMBL27786382 | 0.82 | GPR119 (0.45) | GPR119MAPT | |
| SCHEMBL3636580 | 0.78 | GPR119 (0.83) | HRH3KCNH2GPR119USP30 | |
| SCHEMBL18924338 | 0.77 | HRH3 (0.70) | HRH3KCNH2GPR119SMN1; SMN2KDM4E | |
| SCHEMBL8368604 | 0.76 | HRH3 (0.70) | HRH3KCNH2GPR119MGLLUSP30 | |
| SCHEMBL3728198 | 0.75 | GPR119 (0.77) | HRH3KCNH2GPR119USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101778838-A | Azacyclylbenzamide derivatives as histamine-3 antagonists | WYETH CORP | 2010-07-14 | — | — | CN | disclosed |