Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 8/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4012771 | 0.86 | ADRA1D (0.39) | ADRA1DADRA1AADRA1BADRA2AKDM4E | |
| SCHEMBL1512139 | 0.84 | ADRA1D (0.40) | ADRA1DADRA1AADRA1BADRA2AKDM4E | |
| SCHEMBL13180014 | 0.82 | KDM4E (0.42) | ADRA1DADRA1AADRA1BADRA2AKDM4E | |
| SCHEMBL1151001 | 0.80 | ADRA1D (0.40) | ADRA1DADRA1AADRA1BADRA2AKDM4E | |
| SCHEMBL1150461 | 0.80 | CA2 (0.48) | ADRA1DADRA1AADRA1BADRA2AKDM4E | |
| SCHEMBL5124506 | 0.79 | MAOA (0.39) | ADRA1DADRA1AADRA1BADRA2AKDM4E | |
| Hydrochloric Acid SCHEMBL1017408 | 0.77 | MAOA (0.40) | ADRA1DADRA1AADRA1BADRA2AKDM4E | |
| SCHEMBL13243782 | 0.76 | ADRA1D (0.37) | ADRA1DADRA1AADRA1BADRA2AKDM4E | |
| SCHEMBL6077312 | 0.76 | ADRA1D (0.43) | ADRA1DADRA1AADRA1BADRA2ACCR2 | |
| SCHEMBL1151151 | 0.75 | CA12 (0.43) | ADRA1DADRA1AADRA1BKDM4EDDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101541751-A | Quinoline compounds | WYETH CORP (US) | 2009-09-23 | — | — | CN | disclosed |