Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.63 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.55 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.55 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.55 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.55 |
| ▸ | XDH | P47989 | 1/20 | 0.55 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.55 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28007259 | 0.97 | CLK4 (0.61) | CLK4GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL2154026 | 0.97 | CLK4 (0.65) | CLK4GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL270874 | 0.95 | GABRG2 (0.61) | CLK4GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL29425207 | 0.95 | GABRG2 (0.61) | CLK4GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL18411368 | 0.93 | GABRG2 (0.59) | CLK4GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL21189130 | 0.93 | CLK4 (0.57) | CLK4GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL18411383 | 0.93 | GABRG2 (0.59) | CLK4GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL693857 | 0.89 | CLK4 (0.53) | CLK4GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL29511815 | 0.89 | XDH (0.56) | CLK4GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL20396126 | 0.89 | XDH (0.56) | CLK4GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440528-A | Fourth Ring Bu Luomo structural domain inhibitor | 艾伯维公司 | 2018-08-24 | — | — | CN | claimed |
| CN-105026403-B | Tetracyclic Bromodomain Inhibitors | 艾伯维公司 | 2018-05-18 | — | — | CN | claimed |
| CN-105026403-A | Tetracyclic bromodomain inhibitors | ABBVIE INC | 2015-11-04 | — | — | CN | claimed |
| CN-109400708-A | The antibody and application thereof of Olanzapine haptens | 詹森药业有限公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-104755093-B | Antibodies to olanzapine haptens and uses thereof | 詹森药业有限公司 | 2018-11-16 | — | — | CN | disclosed |
| CN-108440528-A | Fourth Ring Bu Luomo structural domain inhibitor | 艾伯维公司 | 2018-08-24 | — | — | CN | disclosed |
| CN-105026403-B | Tetracyclic Bromodomain Inhibitors | 艾伯维公司 | 2018-05-18 | — | — | CN | disclosed |
| CN-105026403-A | Tetracyclic bromodomain inhibitors | ABBVIE INC | 2015-11-04 | — | — | CN | disclosed |
| CN-104854110-A | Olanzapine haptens | JANSSEN PHARMACEUTICA NV | 2015-08-19 | — | — | CN | disclosed |
| CN-104755093-A | Antibodies to olanzapine haptens and uses thereof | ORTHO CLINICAL DIAGNOSTICS INC | 2015-07-01 | — | — | CN | disclosed |
| CN-101541811-B | Pyrazolopyrimidine Derivatives | DAIICHI SANKYO CO LTD | 2014-07-09 | — | — | CN | disclosed |
| CN-101541811-A | Pyrazolopyrimidine Derivatives | DAIICHI SANKYO CO LTD (JP) | 2009-09-23 | — | — | CN | disclosed |