SCHEMBL270874

SCHEMBL270874

N#Cc1cccc(-c2ccccc2)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRG2 P18507 3/20 0.61
GABRB3 P28472 3/20 0.61
GABRA5 P31644 3/20 0.61
GABRA3 P34903 3/20 0.61
GABRA1 P14867 1/20 0.61
TSHR P16473 1/20 0.59
CLK4 Q9HAZ1 1/20 0.59
XDH P47989 1/20 0.56
SLC22A12 Q96S37 1/20 0.56
PTPN5 P54829 1/20 0.56
ADORA2A P29274 3/20 0.54
ADORA1 P30542 2/20 0.54
ALDH1A3 P47895 1/20 0.53
ADRA2C P18825 1/20 0.51
IDO1 P14902 2/20 0.50
NOTUM Q6P988 1/20 0.50
ADORA2B P29275 1/20 0.50
MAOB P27338 1/20 0.50
CHEK1 O14757 1/20 0.50
MMP12 P39900 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29425207 1.00 GABRG2 (0.61) GABRG2GABRB3GABRA5GABRA3GABRA1
SCHEMBL18411383 0.98 GABRG2 (0.59) GABRG2GABRB3GABRA5GABRA3GABRA1
SCHEMBL18411368 0.98 GABRG2 (0.59) GABRG2GABRB3GABRA5GABRA3GABRA1
SCHEMBL27787243 0.95 CLK4 (0.63) GABRG2GABRB3GABRA5GABRA3GABRA1
SCHEMBL20396126 0.94 XDH (0.56) GABRG2GABRB3GABRA5GABRA3GABRA1
SCHEMBL29511815 0.94 XDH (0.56) GABRG2GABRB3GABRA5GABRA3GABRA1
Biphenyl SCHEMBL29234256 0.93 TSHR (0.62) GABRG2GABRB3GABRA5GABRA3GABRA1
Hydrochloric Acid SCHEMBL28007259 0.93 CLK4 (0.61) GABRG2GABRB3GABRA5GABRA3GABRA1
SCHEMBL2154026 0.93 CLK4 (0.65) GABRG2GABRB3GABRA5GABRA3GABRA1
Phenol SCHEMBL28023686 0.90 XDH (0.57) GABRG2GABRB3GABRA5GABRA3GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 405 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240423011-A1 PLANAR LIGHT-EMITTING TRANSISTOR DEVICE CAPABLE OF SURFACE LIGHT SOURCE EMISSION, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2024-12-19 US claimed
CN-113024530-B Isatin-1, 2, 4-oxadiazole compound and preparation method and application thereof 合肥工业大学 2023-07-18 CN claimed
WO-2023078156-A1 PLANAR LIGHT-EMITTING TRANSISTOR DEVICE CAPABLE OF SURFACE LIGHT SOURCE EMISSION, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 中国科学院化学研究所 2023-05-11 WO claimed
CN-113594378-A Light emitting layer material, light emitting device, and light emitting apparatus 广东聚华印刷显示技术有限公司 2021-11-02 CN claimed
CN-113024530-A Isatin-1, 2, 4-oxadiazole compound and preparation method and application thereof 合肥工业大学 2021-06-25 CN claimed
CN-111883676-A Electroluminescent device and display device 广东聚华印刷显示技术有限公司 2020-11-03 CN claimed
CN-111883677-A Hybrid light emitting device and display apparatus 广东聚华印刷显示技术有限公司 2020-11-03 CN claimed
CN-111883678-A Electroluminescent device and display device 广东聚华印刷显示技术有限公司 2020-11-03 CN claimed
CN-108863894-B Method for directly synthesizing indole from nitrile 中国科学技术大学 2020-08-14 CN claimed
CN-105102449-B Antiviral compound 豪夫迈·罗氏有限公司 2017-06-13 CN claimed
EP-1667958-A2 MELANIN CONCENTRATING HORMONE ANTAGONISTS THE PROCTER & GAMBLE COMPANY (US) 2006-06-14 EP claimed
WO-2005033063-A2 MELANIN CONCENTRATING HORMONE ANTAGONISTS THE PROCTER & GAMBLE COMPANY (US) 2005-04-14 WO claimed
US-20050075324-A1 Melanin concentrating hormone antagonists THE PROCTER & GAMBLE COMPANY (US) 2005-04-07 US claimed
EP-1509497-A1 CALCIUM RECEPTOR MODULATING ARYLALKYLAMINES Amgen Inc. (US) 2005-03-02 EP claimed
CN-1498218-A Imidazo-pyrimidine derivatives as GABA receptor ligands Ĭ�ˡ�����-��ķ��˾ 2004-05-19 CN claimed
CN-1487924-A Farnesyl transferase inhibitors ���Ͽع����޹�˾ 2004-04-07 CN claimed
WO-2003099776-A1 CALCIUM RECEPTOR MODULATING ARYLALKYLAMINES AMGEN INC. (US) 2003-12-04 WO claimed
EP-1339695-A1 FARNESYLTRANSFERASE INHIBITORS Abbott Laboratories (US) 2003-09-03 EP claimed
WO-2002074747-A1 FARNESYLTRANSFERASE INHIBITORS ABBOTT LABORATORIES (US) 2002-09-26 WO claimed
EP-0913725-A1 Optically adressed spatial light modulator with a polymeric-liquid crystal structure COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1999-05-06 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050075324-A1 Melanin concentrating hormone antagonists MCHR1, MCHR2, MC1R GABRG2 422/4885GABRB3 389/4885GABRA5 192/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.