Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | FYN | P06241 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10806221 | 0.85 | OPRM1 (0.42) | OPRM1OPRD1OPRK1GRM2GRM3 | |
| SCHEMBL28985548 | 0.84 | SLC1A3 (0.43) | OPRM1OPRD1OPRK1GRM2GRM3 | |
| SCHEMBL27721177 | 0.84 | OPRM1 (0.44) | OPRM1OPRD1OPRK1GRM2GRM3 | |
| SCHEMBL20347200 | 0.78 | CTSS (0.43) | OPRM1OPRD1OPRK1GRM2GRM3 | |
| SCHEMBL20791731 | 0.77 | OPRM1 (0.54) | OPRM1OPRD1OPRK1CTSSCTSK | |
| SCHEMBL20350621 | 0.77 | SLC1A3 (0.41) | OPRM1OPRD1OPRK1GRM2GRM3 | |
| SCHEMBL5844759 | 0.76 | TAAR1 (0.43) | OPRM1OPRD1OPRK1GRM2GRM3 | |
| SCHEMBL27476791 | 0.76 | CTSS (0.46) | OPRM1OPRD1OPRK1GRM2GRM3 | |
| SCHEMBL73959 | 0.76 | TAAR1 (0.46) | OPRM1OPRD1OPRK1TDP1NPC1 | |
| SCHEMBL23710368 | 0.75 | CYP1A2 (0.42) | OPRM1OPRD1OPRK1GRM2GRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101605777-A | Imidazoles as aldosterone synthase inhibitors | NOVARTIS AG (CH) | 2009-12-16 | — | — | CN | disclosed |