SCHEMBL73959

SCHEMBL73959

CC(C)(C)Cc1ccsc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.46
ESR1 P03372 1/20 0.43
DRD2 P14416 2/20 0.42
DRD3 P35462 2/20 0.42
MEN1 O00255 1/20 0.39
KDM4A O75164 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
HSD17B10 Q99714 1/20 0.39
KDM4C Q9H3R0 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
NPC1 O15118 2/20 0.36
OPRM1 P35372 3/20 0.36
OPRD1 P41143 3/20 0.36
OPRK1 P41145 3/20 0.36
SLC6A2 P23975 2/20 0.34
SLC6A3 Q01959 1/20 0.34
RAB9A P51151 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3802562 0.84 SLC6A2 (0.52) TAAR1DRD2DRD3MEN1KDM4A
SCHEMBL5844759 0.82 TAAR1 (0.43) TAAR1DRD2DRD3MEN1KDM4A
SCHEMBL20711068 0.80 DRD2 (0.43) TAAR1DRD2DRD3MEN1KDM4A
SCHEMBL24119329 0.80 TAAR1 (0.35) TAAR1DRD2DRD3MEN1KDM4A
SCHEMBL12561907 0.77 TAAR1 (0.54) TAAR1DRD2DRD3MEN1KDM4A
SCHEMBL7354627 0.77 DRD2 (0.41) TAAR1DRD2DRD3MEN1KDM4A
SCHEMBL19824759 0.77 DRD2 (0.44) TAAR1ESR1DRD2DRD3MEN1
SCHEMBL7354633 0.77 MEN1 (0.47) TAAR1DRD2DRD3MEN1KDM4A
SCHEMBL18888538 0.77 TAAR1 (0.44) TAAR1DRD2DRD3MEN1KDM4A
SCHEMBL20791731 0.76 OPRM1 (0.54) MEN1ALDH1A1KMT2AKDM4CL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 221 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118791531-A Organic electroluminescent material and device 环球展览公司 2024-10-18 CN disclosed
CN-118772211-A Organic electroluminescent material and device 环球展览公司 2024-10-15 CN disclosed
CN-112552350-B Organic electroluminescent material and device 环球展览公司 2024-06-28 CN disclosed
US-20240026358-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2024-01-25 US disclosed
US-11753371-B2 Disulfiram derivatives as ALDH1A1 and MAGL inhibitors BATTERJEE MEDICAL COLLEGE (SA) 2023-09-12 US disclosed
US-11753371-B2 Disulfiram derivatives as ALDH1A1 and MAGL inhibitors BATTERJEE MEDICAL COLLEGE (SA) 2023-09-12 US disclosed
US-11708458-B2 Composition for thiol-ene-based polymerization and liquid crystalline network-containing objects formed therefrom using additive manufacturing UT-BATTELLE, LLC (US) 2023-07-25 US disclosed
US-20230227428-A1 AMIDO COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2023-07-20 US disclosed
US-20230203484-A1 DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO WAVE LIFE SCIENCES LTD. (SG) 2023-06-29 US disclosed
US-20230203087-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2023-06-29 US disclosed
US-20070155730-A1 Benzodiazepine And Benzopiperazine Analog Inhibitors Of Histone Deacetylase METHYLGENE, INC. (CA) 2007-07-05 US disclosed
US-20070155737-A1 Heterobicyclic metalloprotease inhibitors ALANTOS PHARMACEUTICALS, INC. 2007-07-05 US disclosed
US-7238670-B2 Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions BRISTOL-MYERS SQUIBB COMPANY (US) 2007-07-03 US disclosed
US-7238670-B2 Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions BRISTOL-MYERS SQUIBB COMPANY (US) 2007-07-03 US disclosed
US-7208501-B2 Quinuclidine carbamate derivatives and their use as M3 antagonists ALMIRALL PRODESFARMA AG (CH) 2007-04-24 US disclosed
US-20070049621-A1 6-Alkylamino-2-methyl-2'-(N-methyl substituted sulfonamido)methyl-2H-1-benzopyran derivative as anti-inflammatory inhibitor KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY 2007-03-01 US disclosed
US-20070021331-A1 Methods of using macrocyclic modulators of the ghrelin receptor TRANZYME PHARMA INC. 2007-01-25 US disclosed
US-20040072849-A1 Dioxanes and uses thereof NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2004-04-15 US disclosed
US-4711742-A Solution processible forms of neutral and electrically conductive poly(substituted heterocycles) ALLIED CORPORATION (US) 1987-12-08 US disclosed
EP-0203438-A1 Solution processible forms of neutral and electrically conductive poly(substituted heterocycles) ALLIED CORPORATION (US) 1986-12-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070049621-A1 6-Alkylamino-2-methyl-2'-(N-methyl substituted sulfonamido)methyl-2H-1-benzopyran derivative as anti-inflammatory inhibitor LTA4H, LTC4S, LTB4R TAAR1 2899/4885ESR1 2496/4885DRD2 1016/4885
US-20070155737-A1 Heterobicyclic metalloprotease inhibitors ADAMTS4, ADAMTS1, ADAMTS5 TAAR1 4276/4885ESR1 4336/4885DRD2 4763/4885
US-20230227428-A1 AMIDO COMPOUNDS RIPK1, RIPK3, MLKL TAAR1 3698/4885ESR1 2010/4885DRD2 3854/4885
US-11753371-B2 Disulfiram derivatives as ALDH1A1 and MAGL inhibitors ALDH1A1, ADH1A, ALDH3A1 TAAR1 487/4885ESR1 1569/4885DRD2 726/4885
US-20230203087-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF RNGTT, NSUN2, ALKBH1 TAAR1 4361/4885ESR1 2025/4885DRD2 3994/4885
US-20040072849-A1 Dioxanes and uses thereof UTS2R, HDAC5, AMDHD2 TAAR1 4319/4885ESR1 2541/4885DRD2 3983/4885
US-20070021331-A1 Methods of using macrocyclic modulators of the ghrelin receptor GHSR, GHRHR, GIPR TAAR1 643/4885ESR1 534/4885DRD2 1855/4885
US-20070155730-A1 Benzodiazepine And Benzopiperazine Analog Inhibitors Of Histone Deacetylase HDAC5, HDAC4, HDAC3 TAAR1 906/4885ESR1 1251/4885DRD2 127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.