Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.55 |
| ▸ | TDO2 | P48775 | 1/20 | 0.49 |
| ▸ | DPYD | Q12882 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | RRM1 | P23921 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27905753 | 0.80 | TRPA1 (0.47) | TRPA1DPYDKDM4EALDH1A1 | |
| SCHEMBL6046307 | 0.80 | NFKB1 (0.56) | TDO2KDM4EMEN1RAB9AKMT2A | |
| SCHEMBL6046306 | 0.80 | NFKB1 (0.56) | TDO2KDM4EMEN1RAB9AKMT2A | |
| SCHEMBL9731718 | 0.76 | EGFR (0.46) | TDO2KDM4EKMT2AMAPTALDH1A1 | |
| SCHEMBL2461966 | 0.75 | RAB9A (0.69) | DPYDMEN1USP2RAB9AKMT2A | |
| SCHEMBL29955386 | 0.75 | TRIM24 (0.66) | KMT2ARRM1 | |
| SCHEMBL2461963 | 0.75 | RAB9A (0.69) | DPYDMEN1USP2RAB9AKMT2A | |
| SCHEMBL27992 | 0.72 | TRPA1 (1.00) | TRPA1KDM4ELMNAMAPT | |
| SCHEMBL27991 | 0.72 | TRPA1 (1.00) | TRPA1KDM4ELMNAMAPT | |
| SCHEMBL30218372 | 0.72 | TRPA1 (1.00) | TRPA1KDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850324-A | Indole compounds | MICROBIA INC | 2013-01-02 | — | — | CN | disclosed |
| CN-101563337-A | Indole compounds | MICROBIA INC (US) | 2009-10-21 | — | — | CN | disclosed |