Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ELOVL1 | Q9BW60 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1063920 | 0.88 | CYP2C9 (0.61) | CYP2C9MAPTTSHRHTTHSD17B10 | |
| SCHEMBL725497 | 0.85 | CYP2C9 (0.53) | CYP2C9MAPTTSHRHTTHSD17B10 | |
| SCHEMBL27360401 | 0.85 | CYP2C9 (0.53) | CYP2C9MAPTTSHRHTTHSD17B10 | |
| SCHEMBL4473648 | 0.85 | MAPT (0.58) | CYP2C9MAPTTSHRHTTHSD17B10 | |
| SCHEMBL27768527 | 0.82 | ELOVL1 (0.39) | CYP2C9MAPTTSHRHTTHSD17B10 | |
| SCHEMBL18997594 | 0.80 | ELOVL1 (0.50) | CYP2C9MAPTTSHRHTTHSD17B10 | |
| SCHEMBL1062877 | 0.80 | ELOVL1 (0.50) | CYP2C9MAPTTSHRHTTHSD17B10 | |
| SCHEMBL17321495 | 0.80 | ELOVL1 (0.50) | CYP2C9MAPTTSHRHTTHSD17B10 | |
| SCHEMBL15401858 | 0.80 | MAPT (0.54) | CYP2C9MAPTTSHRHTTHSD17B10 | |
| SCHEMBL28241581 | 0.80 | GAA (0.50) | CYP2C9MAPTTSHRHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108251063-A | A kind of high-performance composite phase-change material and preparation method thereof | 北京有色金属研究总院 | 2018-07-06 | — | — | CN | claimed |
| CN-105492429-A | Heteroaryl inhibitors of SUMO activating enzyme | MILLENNIUM PHARM INC | 2016-04-13 | — | — | CN | disclosed |
| CN-102850324-A | Indole compounds | MICROBIA INC | 2013-01-02 | — | — | CN | disclosed |
| CN-101563337-A | Indole compounds | MICROBIA INC (US) | 2009-10-21 | — | — | CN | disclosed |