Sugi Predict

Sugi Predict / Compounds / SCHEMBL1063920

SCHEMBL1063920

SCHEMBL1063920

O=C(O)c1ccn(-c2ccccc2)n1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP2C9 P11712 2/20 0.61
▸ MAPT P10636 2/20 0.53
▸ TSHR P16473 1/20 0.53
▸ HTT P42858 1/20 0.53
▸ HSD17B10 Q99714 1/20 0.53
▸ L3MBTL1 Q9Y468 1/20 0.53
▸ GAA P10253 1/20 0.49
▸ ELOVL1 Q9BW60 5/20 0.47
▸ LMNA P02545 1/20 0.46
▸ RPA1 P27694 1/20 0.46
▸ HPGDS O60760 1/20 0.46
▸ ALKBH2 Q6NS38 1/20 0.46
▸ ALDH1A1 P00352 2/20 0.45
▸ KDM4E B2RXH2 1/20 0.45
▸ NPC1 O15118 1/20 0.45
▸ SMN1; SMN2 Q16637 1/20 0.45
▸ HDAC3 O15379 1/20 0.44
▸ HDAC1 Q13547 1/20 0.44
▸ HDAC2 Q92769 1/20 0.44
▸ HDAC10 Q969S8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27790040 0.88 CYP2C9 (0.56) CYP2C9MAPTTSHRHTTHSD17B10
SCHEMBL4473648 0.85 MAPT (0.58) CYP2C9MAPTTSHRHTTHSD17B10
SCHEMBL27360401 0.85 CYP2C9 (0.53) CYP2C9MAPTTSHRHTTHSD17B10
SCHEMBL725497 0.85 CYP2C9 (0.53) CYP2C9MAPTTSHRHTTHSD17B10
SCHEMBL31031032 0.85 KMT2A (0.45) CYP2C9MAPTTSHRLMNARPA1
SCHEMBL1816062 0.85 CYP2C9 (0.45) CYP2C9MAPTTSHRHTTHSD17B10
SCHEMBL27498827 0.84 CYP2C9 (0.47) CYP2C9MAPTTSHRHTTHSD17B10
SCHEMBL14150735 0.83 KMT2A (0.64) CYP2C9MAPTL3MBTL1KDM4EKMT2A
SCHEMBL15754423 0.83 RPA1 (0.50) CYP2C9MAPTTSHRL3MBTL1GAA
SCHEMBL31587999 0.83 POLB (0.58) CYP2C9L3MBTL1LMNAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103929964-A Use of 4-substituted 1-phenyl-pyrazole-3-carboxylic-acid derivatives as agents against abiotic plant stress BAYER IP GMBH 2014-07-16 — — CN claimed
US-7842696-B2 Piperazine derivatives as inhibitors of stearoyl-CoA desaturase FOREST LABORATORIES HOLDINGS LIMITED (BM) 2010-11-30 — — US claimed
US-20090221583-A1 NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE FOREST LABORATORIES HOLDINGS LIMITED (BM) 2009-09-03 — — US claimed
CN-101511828-A Heteroaryl derivatives as protein kinase inhibitors HOFFMANN LA ROCHE (CH) 2009-08-19 — — CN claimed
EP-1515606-A2 COMBINATIONS OF HERBICIDAL AROMATIC CARBOXYLIC ACIDS AND SAFENERS Bayer CropScience GmbH (DE) 2005-03-23 — — EP claimed
WO-2003103394-A2 COMBINATIONS OF HERBICIDAL AROMATIC CARBOXYLIC ACIDS AND SAFENERS BAYER CROPSCIENCE GMBH (DE) 2003-12-18 — — WO claimed
US-20030232725-A1 Combinations of herbicidal aromatic carboxylic acids and safeners BAYER CROPSCIENCE AG (DE) 2003-12-18 — — US claimed
WO-2001043546-A2 COMBINATIONS OF HERBICIDAL ALKYLAZINES AND SAFENERS AVENTIS CROPSCIENCE GMBH (DE) 2001-06-21 — — WO claimed
CN-1184469-A 1-phenyl-3-pyrazolecarboxamides active on neurotensin receptors SANOFI SA (FR) 1998-06-10 — — CN claimed
EP-3856179-B1 MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2026-05-13 — — EP disclosed
EP-4642782-A2 ALPHA-V-BETA-8 INTEGRIN INHIBITORS AND USES THEREOF Pliant Therapeutics, Inc. (US) 2025-11-05 — — EP disclosed
US-12297209-B2 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2025-05-13 — — US disclosed
WO-2025096662-A1 COMPOSITIONS AND INHIBITORS OF POLRMT PRETZEL THERAPEUTICS, INC. (US) 2025-05-08 — — WO disclosed
WO-2025096658-A1 COMPOSITIONS AND INHIBITORS OF POLRMT PRETZEL THERAPEUTICS, INC. (US) 2025-05-08 — — WO disclosed
CN-1184469-A 1-phenyl-3-pyrazolecarboxamides active on neurotensin receptors SANOFI SA (FR) 1998-06-10 — — CN disclosed
US-5723483-A NEUROTENSIN ANTAGONIST, HYPOTENSIVE AGENTS AND FOR NEUROPSYCHIATRIC DISORDERS SANOFI (FR) 1998-03-03 — — US disclosed
US-5082949-A Plant growth regulators, protective agents HOECHST AKTIENGESELLSCHAFT (DE) 1992-01-21 — — US disclosed
US-4891057-A Phenylpyrazolecarboxylic acid derivatives, their preparation, and their use as plant-growth regulators and safeners HOECHST AKTIENGESELLSCHAFT (DE) 1990-01-02 — — US disclosed
US-4891057-A Phenylpyrazolecarboxylic acid derivatives, their preparation, and their use as plant-growth regulators and safeners HOECHST AKTIENGESELLSCHAFT (DE) 1990-01-02 — — US disclosed
US-4265632-A Process for the coloration of thermoplastic polymers and polycondensates in the mass with water-insoluble disazomethine compounds HOECHST AKTIENGESELLSCHAFT (DE) 1981-05-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12297209-B2 Benzodiazepine derivatives as RSV inhibitors GABRA5, GABRA1, GABBR2 CYP2C9 62/4885MAPT 2157/4885TSHR 1396/4885
US-20030232725-A1 Combinations of herbicidal aromatic carboxylic acids and safeners DDT, CYP2W1, AADAC CYP2C9 199/4885MAPT 4556/4885TSHR 48/4885
US-20090221583-A1 NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE SCD, SCD5, FADS2 CYP2C9 3031/4885MAPT 3595/4885TSHR 4601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.