Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ELOVL1 | Q9BW60 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27790040 | 0.85 | CYP2C9 (0.56) | CYP2C9MAPTTSHRHTTHSD17B10 | |
| SCHEMBL1063920 | 0.85 | CYP2C9 (0.61) | CYP2C9MAPTTSHRHTTHSD17B10 | |
| SCHEMBL31587160 | 0.84 | ALDH1A1 (0.50) | CYP2C9MAPTL3MBTL1LMNAGAA | |
| SCHEMBL4473648 | 0.81 | MAPT (0.58) | CYP2C9MAPTTSHRHTTHSD17B10 | |
| SCHEMBL725497 | 0.81 | CYP2C9 (0.53) | CYP2C9MAPTTSHRHTTHSD17B10 | |
| SCHEMBL18997594 | 0.77 | ELOVL1 (0.50) | CYP2C9MAPTTSHRHTTHSD17B10 | |
| SCHEMBL15401858 | 0.77 | MAPT (0.54) | CYP2C9MAPTTSHRHTTHSD17B10 | |
| SCHEMBL1062877 | 0.77 | ELOVL1 (0.50) | CYP2C9MAPTTSHRHTTHSD17B10 | |
| SCHEMBL17321495 | 0.77 | ELOVL1 (0.50) | CYP2C9MAPTTSHRHTTHSD17B10 | |
| SCHEMBL28662399 | 0.77 | CYP2C9 (0.76) | CYP2C9MAPTTSHRHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1072210-C | 1-phenyl-3-pyrazolecarboxamides active on neurotensin receptors | SANOFI SYNTHELABO (FR) | 2001-10-03 | — | — | CN | disclosed |