Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | RET | P07949 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | KDR | P35968 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NQO1 | P15559 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Xylocoumarol SCHEMBL2111715 | 0.89 | MAOB (0.62) | MAOBKDM4ELMNATP53TSHR | |
| SCHEMBL669375 | 0.87 | MAOB (0.70) | MAOBKDM4ELMNATP53TSHR | |
| SCHEMBL29466790 | 0.87 | MAOB (0.70) | MAOBKDM4ELMNATP53TSHR | |
| SCHEMBL14506703 | 0.85 | MAOB (0.55) | MAOBKDM4ELMNATP53TSHR | |
| SCHEMBL11480850 | 0.84 | MAOB (0.68) | MAOBKDM4ELMNATP53TSHR | |
| SCHEMBL8934636 | 0.84 | MAOB (0.68) | MAOBKDM4ELMNATP53TSHR | |
| SCHEMBL11480111 | 0.84 | MAOB (0.68) | MAOBKDM4ELMNATP53TSHR | |
| SCHEMBL11485562 | 0.84 | MAOB (1.00) | MAOBKDM4ELMNATP53ALDH1A1 | |
| SCHEMBL13769238 | 0.83 | MAOB (0.53) | MAOBKDM4ELMNATP53TSHR | |
| SCHEMBL11480049 | 0.82 | MAOB (0.71) | MAOBKDM4ETP53HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101817830-B | Method for synthesizing Coumestan derivatives | UNIV TIANJIN | 2011-09-28 | — | — | CN | disclosed |
| CN-101817830-A | Method for synthesizing Coumestan derivatives | UNIV TIANJIN | 2010-09-01 | — | — | CN | disclosed |