Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | NQO1 | P15559 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.57 |
| ▸ | PCSK7 | Q16549 | 1/20 | 0.57 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29466790 | 1.00 | MAOB (0.70) | MAOBKDM4ENQO1MEN1LMNA | |
| SCHEMBL8934636 | 0.87 | MAOB (0.68) | MAOBKDM4ENQO1MEN1LMNA | |
| SCHEMBL27790298 | 0.87 | MAOB (0.72) | MAOBKDM4ENQO1MEN1LMNA | |
| SCHEMBL11480111 | 0.87 | MAOB (0.68) | MAOBKDM4ENQO1MEN1LMNA | |
| SCHEMBL11480850 | 0.87 | MAOB (0.68) | MAOBKDM4ENQO1MEN1LMNA | |
| SCHEMBL28143419 | 0.86 | KDM4E (0.56) | MAOBKDM4ENQO1MEN1LMNA | |
| SCHEMBL11477219 | 0.83 | ERAP1 (0.61) | MAOBKDM4EMEN1TP53CYP3A4 | |
| SCHEMBL11478035 | 0.83 | ERAP1 (0.74) | MAOBKDM4ENQO1MEN1LMNA | |
| SCHEMBL1800595 | 0.83 | CA1 (0.56) | MAOBKDM4ENQO1MEN1LMNA | |
| SCHEMBL9210163 | 0.83 | MAOB (0.63) | MAOBKDM4ENQO1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269351-A | Compounds for inhibiting fucosylation and methods of use thereof | 思科医药公司 | 2022-04-01 | — | — | CN | claimed |
| CN-106107406-B | Methods of improving the stability of sweetness enhancers and compositions comprising stable sweetness enhancers | 弗门尼舍公司 | 2020-06-09 | — | — | CN | claimed |
| CN-106107406-A | Improve the method for the stability of sweetness enhancers and comprise the compositions of stable sweetness enhancers | 赛诺米克斯公司 | 2016-11-16 | — | — | CN | claimed |
| CN-118695854-A | Food-related particles, production method and production device | 努利希尔有限公司 | 2024-09-24 | — | — | CN | disclosed |
| CN-106107406-B | Methods of improving the stability of sweetness enhancers and compositions comprising stable sweetness enhancers | 弗门尼舍公司 | 2020-06-09 | — | — | CN | disclosed |
| US-9556382-B2 | Polymerisable mixtures and the use thereof in liquid crystal displays | MERCK PATENT GMBH (DE) | 2017-01-31 | — | — | US | disclosed |
| EP-2596034-B1 | POLYMERIZABLE MIXTURES AND THE USE THEREOF IN LIQUID CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2014-11-26 | — | — | EP | disclosed |
| US-8592007-B2 | Liquid-crystal display | MERCK PATENT GMBH (DE) | 2013-11-26 | — | — | US | disclosed |
| EP-2596034-A2 | POLYMERIZABLE MIXTURES AND THE USE THEREOF IN LIQUID CRYSTAL DISPLAYS | Merck Patent GmbH (DE) | 2013-05-29 | — | — | EP | disclosed |
| EP-2340292-B1 | LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2013-05-29 | — | — | EP | disclosed |
| US-20130114010-A1 | POLYMERISABLE MIXTURES AND THE USE THEREOF IN LIQUID CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2013-05-09 | — | — | US | disclosed |
| US-5585357-A | Heteroaryloxymethyl ketones as interleukin-1βconverting enzyme inhibitors | SANOFI WINTHROP INC. (US) | 1996-12-17 | — | — | US | disclosed |
| EP-0644198-A1 | Alpha-heteroaryloxymethyl ketones as interleukin-1beta converting enzyme inhibitors | STERLING WINTHROP INC. (US) | 1995-03-22 | — | — | EP | disclosed |
| EP-0244309-B1 | RODENTICIDAL COMPOSITIONS CONTAINING 1,4-NAPHTHOQUINONE DERIVATIVES | DUKE UNIVERSITY (US) | 1993-02-03 | — | — | EP | disclosed |
| EP-0244309-A2 | Rodenticidal compositions containing 1,4-naphthoquinone derivatives | DUKE UNIVERSITY (US) | 1987-11-04 | — | — | EP | disclosed |
| EP-0091141-B1 | PROCESS FOR THE PREPARATION OF THIOETHERS | GIST-BROCADES N.V. (NL) | 1985-07-31 | — | — | EP | disclosed |
| US-4496720-A | REACTING SILATED THIO WITH ORGANIC HALIDE, SULATE OR SULFONATE IN PRESENCE OF HEXAMETHYLPHOSPHORIC TRIAMIDE | GIST-BROCADES N.V. (NL) | 1985-01-29 | — | — | US | disclosed |
| EP-0091141-A1 | Process for the preparation of thioethers | GIST-BROCADES N.V. (NL) | 1983-10-12 | — | — | EP | disclosed |
| EP-0088831-A1 | Process for the preparation of thioethers | GIST-BROCADES N.V. (NL) | 1983-09-21 | — | — | EP | disclosed |
| US-4230850-A | HYPOTENSIVE AGENTS, VASODILATION | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1980-10-28 | — | — | US | disclosed |