SCHEMBL29466790

SCHEMBL29466790

O=c1oc2ccccc2c(O)c1-c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.70
KDM4E B2RXH2 2/20 0.59
NQO1 P15559 6/20 0.57
MEN1 O00255 2/20 0.57
LMNA P02545 2/20 0.57
TP53 P04637 2/20 0.57
CYP3A4 P08684 2/20 0.57
MAPK1 P28482 2/20 0.57
KMT2A Q03164 2/20 0.57
CYP2C9 P11712 2/20 0.57
ABCB11 O95342 1/20 0.57
ALDH1A1 P00352 1/20 0.57
CYP1A2 P05177 1/20 0.57
TSHR P16473 1/20 0.57
CYP2C19 P33261 1/20 0.57
PDE4D Q08499 1/20 0.57
PCSK7 Q16549 1/20 0.57
GPR35 Q9HC97 1/20 0.57
CA12 O43570 2/20 0.56
CA9 Q16790 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL669375 1.00 MAOB (0.70) MAOBKDM4ENQO1MEN1LMNA
SCHEMBL8934636 0.87 MAOB (0.68) MAOBKDM4ENQO1MEN1LMNA
SCHEMBL27790298 0.87 MAOB (0.72) MAOBKDM4ENQO1MEN1LMNA
SCHEMBL11480111 0.87 MAOB (0.68) MAOBKDM4ENQO1MEN1LMNA
SCHEMBL11480850 0.87 MAOB (0.68) MAOBKDM4ENQO1MEN1LMNA
SCHEMBL28143419 0.86 KDM4E (0.56) MAOBKDM4ENQO1MEN1LMNA
SCHEMBL11477219 0.83 ERAP1 (0.61) MAOBKDM4EMEN1TP53CYP3A4
SCHEMBL11478035 0.83 ERAP1 (0.74) MAOBKDM4ENQO1MEN1LMNA
SCHEMBL1800595 0.83 CA1 (0.56) MAOBKDM4ENQO1MEN1LMNA
SCHEMBL9210163 0.83 MAOB (0.63) MAOBKDM4ENQO1MEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4359375-A1 PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY PHENYL COMPOUNDS McMaster University (CA) 2024-05-01 EP claimed
EP-4157811-A1 PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS McMaster University (CA) 2023-04-05 EP claimed
WO-2022266765-A1 PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY PHENYL COMPOUNDS MCMASTER UNIVERSITY (CA) 2022-12-29 WO claimed
US-20240317660-A1 PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY PHENYL COMPOUNDS MCMASTER UNIVERSITY (CA) 2024-09-26 US disclosed
US-20240150269-A1 PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS MCMASTER UNIVERSITY (CA) 2024-05-09 US disclosed
EP-4359375-A1 PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY PHENYL COMPOUNDS McMaster University (CA) 2024-05-01 EP disclosed
US-11795127-B2 Processes for the preparation of ortho-allylated hydroxy aryl compounds MCMASTER UNIVERSITY (CA) 2023-10-24 US disclosed
US-20230113567-A1 PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS MCMASTER UNIVERSITY (CA) 2023-04-13 US disclosed
EP-4157811-A1 PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS McMaster University (CA) 2023-04-05 EP disclosed
CN-115867250-A Skin tightening cosmetic compositions and methods of use 莱雅公司 2023-03-28 CN disclosed
WO-2022266765-A1 PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY PHENYL COMPOUNDS MCMASTER UNIVERSITY (CA) 2022-12-29 WO disclosed
CN-115282158-A Application of glucoside compounds 浙江中医药大学 2022-11-04 CN disclosed
CN-112098563-B Detection method for chemical components of kidney-tonifying and blood-activating formula 中国中医科学院望京医院(中国中医科学院骨伤科研究所) 2022-07-15 CN disclosed
CN-114466651-A Methods of using oral care compositions comprising hops 宝洁公司 2022-05-10 CN disclosed
CN-114466642-A Oral care compositions comprising hops beta acids and fluoride 宝洁公司 2022-05-10 CN disclosed
CN-114466680-A Oral care compositions comprising hops beta acids and amino acids 宝洁公司 2022-05-10 CN disclosed
CN-114449996-A Oral care compositions comprising hops beta acids and metal ions 宝洁公司 2022-05-06 CN disclosed
CN-114449993-A Fluoride-free dental caries-resistant oral care compositions 宝洁公司 2022-05-06 CN disclosed
CN-114449991-A Oral care compositions with anticaries activity 宝洁公司 2022-05-06 CN disclosed
CN-114196707-A Angelica sinensis blood-enriching soup fermentation liquor and preparation method and application thereof 香港科技大学深圳研究院 2022-03-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230113567-A1 PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS ADH1A, ADH1C, AHR MAOB 779/4885KDM4E 2010/4885NQO1 558/4885
US-20240317660-A1 PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY PHENYL COMPOUNDS ADH1A, AHR, ADH1C MAOB 906/4885KDM4E 1560/4885NQO1 656/4885
US-11795127-B2 Processes for the preparation of ortho-allylated hydroxy aryl compounds ADH1A, ADH1C, AHR MAOB 779/4885KDM4E 2010/4885NQO1 558/4885
US-20240150269-A1 PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS ADH1A, ADH1C, AHR MAOB 926/4885KDM4E 2117/4885NQO1 639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.