Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720591 | 0.79 | HTR2C (0.43) | HTR2CPRCPDDB1CRBNHSD11B1 | |
| SCHEMBL8720593 | 0.74 | HTR2C (0.42) | HTR2CPRCPDDB1CRBNHSD11B1 | |
| SCHEMBL8586016 | 0.70 | PRCP (0.41) | HTR2CPRCPDDB1CRBN | |
| SCHEMBL4984854 | 0.70 | ALDH1A1 (0.41) | HTR2CSLC6A2SLC6A4CYP2D6HSD11B1 | |
| SCHEMBL10357087 | 0.69 | SLC6A4 (0.40) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10357086 | 0.69 | SLC6A4 (0.40) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10357084 | 0.69 | SLC6A4 (0.40) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4991857 | 0.69 | GAA (0.46) | HTR2CMAPK1HTR2B | |
| SCHEMBL8945265 | 0.68 | HTR6 (0.36) | HTR2CPRCPMAPK1HTR2AHTR2B | |
| SCHEMBL10743156 | 0.67 | KDM1A (0.38) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101652066-A | hydroxymethyl ether hydroisoindoline tachykinin receptor antagonists | MERCK & CO INC US | 2010-02-17 | — | — | CN | disclosed |