SCHEMBL8586016

SCHEMBL8586016

Cc1ccccc1C1CCCCC1(P)c1ccccc1C

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PRCP P42785 1/20 0.41
HDAC4 P56524 1/20 0.38
HTR2C P28335 2/20 0.36
DDB1 Q16531 1/20 0.34
CRBN Q96SW2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15658975 0.82 HTR2C (0.39) PRCPHTR2C
SCHEMBL8720591 0.79 HTR2C (0.43) PRCPHTR2CDDB1CRBN
SCHEMBL8720593 0.74 HTR2C (0.42) PRCPHTR2CDDB1CRBN
SCHEMBL15655439 0.72 PRCP (0.36) PRCPHDAC4
SCHEMBL21873473 0.70 NFKB1 (0.33) PRCPHDAC4
SCHEMBL27792149 0.70 HTR2C (0.36) PRCPHTR2CDDB1CRBN
SCHEMBL28259692 0.70 HTR2C (0.46) PRCPHDAC4HTR2C
SCHEMBL27854455 0.66 NOS3 (0.39) HTR2CDDB1CRBN
SCHEMBL8945265 0.65 HTR6 (0.36) PRCPHTR2C
SCHEMBL16031140 0.65 HDAC4 (0.41) HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2735581-B1 COMPOSITION AND POLYMER ASAHI CHEMICAL IND (JP) 2021-07-14 EP disclosed
US-9738757-B2 Composition and polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2017-08-22 US disclosed
US-20160222168-A1 Composition and Polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-08-04 US disclosed
US-9334371-B2 Composition and polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-05-10 US disclosed
EP-2735581-A1 COMPOSITION AND POLYMER Asahi Kasei Chemicals Corporation (JP) 2014-05-28 EP disclosed
US-20140121293-A1 Composition and Polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2014-05-01 US disclosed
US-5831107-A Palladacycles and a process for their preparation AVENTIS RESEARCH & TECHNOLOGY DEUTSCHLAND (DE) 1998-11-03 US disclosed