Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.47 |
| ▸ | CYCS | P99999 | 4/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 4/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27814700 | 0.95 | TOP1 (0.48) | TOP1CYCSSTAT3STAT1ENPP2 | |
| SCHEMBL14181444 | 0.89 | MAPT (0.46) | TOP1CYCSSTAT3STAT1ENPP2 | |
| SCHEMBL14350959 | 0.89 | ABCG2 (0.44) | TOP1CYCSENPP2TERTABCG2 | |
| SCHEMBL28355568 | 0.88 | TOP1 (0.49) | TOP1CYCSENPP2TERTABCG2 | |
| SCHEMBL585218 | 0.86 | TERT (0.44) | TOP1CYCSENPP2TERTABCG2 | |
| SCHEMBL588821 | 0.86 | TERT (0.44) | TOP1CYCSENPP2TERTABCG2 | |
| Pyridine SCHEMBL28010654 | 0.83 | CYP2D6 (0.49) | TOP1CYCSSTAT3STAT1TERT | |
| SCHEMBL30739549 | 0.82 | TOP1 (0.42) | TOP1CYCSENPP2TERTABCG2 | |
| SCHEMBL21870670 | 0.81 | TOP1 (0.47) | TOP1CYCSSTAT3STAT1ENPP2 | |
| SCHEMBL14181436 | 0.81 | TOP1 (0.47) | TOP1CYCSSTAT3STAT1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103102353-A | Free porphyrin, and preparation method and application thereof | UNIV NORTHWESTERN | 2013-05-15 | — | — | CN | claimed |
| CN-103102353-A | Free porphyrin, and preparation method and application thereof | UNIV NORTHWESTERN | 2013-05-15 | — | — | CN | disclosed |
| CN-101851256-B | Ruthenium (II) porphyrin complex connected by flexible carbon chain and preparation method and application thereof | UNIV GUANGDONG PHARM | 2013-01-09 | — | — | CN | disclosed |
| CN-101851256-A | Ruthenium (II) porphyrin complex connected by flexible carbon chain and preparation method and application thereof | GUANGDONG PHARMACEUTICAL UNIVERSITY | 2010-10-06 | — | — | CN | disclosed |