Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.47 |
| ▸ | TERT | O14746 | 4/20 | 0.46 |
| ▸ | CYCS | P99999 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14181436 | 1.00 | TOP1 (0.47) | TOP1TERTCYCSL3MBTL1ENPP2 | |
| SCHEMBL14181444 | 0.88 | MAPT (0.46) | TOP1TERTCYCSENPP2ALDH1A1 | |
| SCHEMBL28930641 | 0.83 | TERT (0.44) | TOP1TERTCYCSL3MBTL1ENPP2 | |
| SCHEMBL28689706 | 0.83 | TERT (0.44) | TOP1TERTCYCSL3MBTL1ENPP2 | |
| SCHEMBL28671162 | 0.82 | TERT (0.43) | TOP1TERTCYCSL3MBTL1ENPP2 | |
| SCHEMBL28693190 | 0.82 | TERT (0.43) | TOP1TERTCYCSL3MBTL1ENPP2 | |
| SCHEMBL27793465 | 0.81 | TOP1 (0.47) | TOP1TERTCYCSENPP2STAT3 | |
| SCHEMBL12633085 | 0.80 | TERT (0.47) | TOP1TERTCYCSENPP2ALDH1A1 | |
| SCHEMBL27814700 | 0.80 | TOP1 (0.48) | TOP1TERTCYCSL3MBTL1ENPP2 | |
| SCHEMBL12048587 | 0.79 | TERT (0.43) | TOP1TERTCYCSSTAT3STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11186545-B2 | Phenalene-1-one-containing photosensitizer composition, phenalene-1-one compound and the use thereof | TRIOPTOTEC GMBH (DE) | 2021-11-30 | — | — | US | disclosed |
| US-20200087259-A1 | PHENALENE-1-ONE-CONTAINING PHOTOSENSITIZER COMPOSITION, PHENALENE-1-ONE COMPOUND AND THE USE THEREOF | TRIOPTOTEC GMBH (DE) | 2020-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200087259-A1 | PHENALENE-1-ONE-CONTAINING PHOTOSENSITIZER COMPOSITION, PHENALENE-1-ONE COMPOUND AND THE USE THEREOF | PYCR1, CRY1, PPOX | TOP1 248/4885TERT 1104/4885CYCS 2689/4885 |
| US-11186545-B2 | Phenalene-1-one-containing photosensitizer composition, phenalene-1-one compound and the use thereof | PYCR1, CRY1, PPOX | TOP1 248/4885TERT 1104/4885CYCS 2689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.