Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.48 |
| ▸ | CYCS | P99999 | 4/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 4/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27793465 | 0.95 | TOP1 (0.47) | TOP1CYCSSTAT3STAT1ENPP2 | |
| SCHEMBL30739549 | 0.87 | TOP1 (0.42) | TOP1CYCSENPP2TERTABCG2 | |
| SCHEMBL588821 | 0.87 | TERT (0.44) | TOP1CYCSENPP2TERTABCG2 | |
| SCHEMBL585218 | 0.87 | TERT (0.44) | TOP1CYCSENPP2TERTABCG2 | |
| SCHEMBL14181444 | 0.87 | MAPT (0.46) | TOP1CYCSSTAT3STAT1ENPP2 | |
| SCHEMBL28355568 | 0.86 | TOP1 (0.49) | TOP1CYCSENPP2TERTABCG2 | |
| SCHEMBL14806849 | 0.85 | MAOA (0.40) | TOP1CYCSSTAT3STAT1TERT | |
| SCHEMBL14806867 | 0.85 | MAOA (0.40) | TOP1CYCSSTAT3STAT1TERT | |
| SCHEMBL15939977 | 0.84 | MAOA (0.40) | TOP1CYCSSTAT3STAT1TERT | |
| SCHEMBL14806856 | 0.84 | MAOA (0.40) | TOP1CYCSSTAT3STAT1TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101851256-B | Ruthenium (II) porphyrin complex connected by flexible carbon chain and preparation method and application thereof | UNIV GUANGDONG PHARM | 2013-01-09 | — | — | CN | disclosed |
| CN-101851256-A | Ruthenium (II) porphyrin complex connected by flexible carbon chain and preparation method and application thereof | GUANGDONG PHARMACEUTICAL UNIVERSITY | 2010-10-06 | — | — | CN | disclosed |