Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 4/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10113885 | 0.90 | KMT2A (0.71) | MAPK1CYP1A2ALDH1A1SMN1; SMN2TP53 | |
| Ethylbenzene SCHEMBL28785055 | 0.89 | LMNA (0.66) | MAPK1CYP1A2ALDH1A1SMN1; SMN2NPSR1 | |
| O-Xylene SCHEMBL27814994 | 0.89 | CYP1A2 (0.74) | MAPK1CYP1A2ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL10113976 | 0.84 | LMNA (0.70) | MAPK1CYP1A2SMN1; SMN2TP53RXFP1 | |
| SCHEMBL18166761 | 0.82 | MAPK1 (0.74) | MAPK1CYP1A2ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL20161764 | 0.82 | CYP1A2 (0.71) | MAPK1CYP1A2ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL5462777 | 0.81 | RXFP1 (0.78) | MAPK1CYP1A2SMN1; SMN2TP53RXFP1 | |
| SCHEMBL3826453 | 0.81 | TRPA1 (0.77) | CYP1A2TP53RXFP1ALOX15MEN1 | |
| SCHEMBL4533692 | 0.81 | RXFP1 (0.78) | MAPK1CYP1A2ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL18166673 | 0.81 | CYP1A2 (0.69) | MAPK1CYP1A2TP53RXFP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101801362-B | Methods and compositions for treating disorders | HYDRA BIOSCIENCES INC | 2014-01-22 | — | — | CN | disclosed |
| CN-101801362-A | methods and compositions for treating disorders | HYDRA BIOSCIENCES INC | 2010-08-11 | — | — | CN | disclosed |