Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 4/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.37 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28915633 | 0.84 | TRPA1 (0.57) | TRPA1CYP2D6SLC6A2TAAR1SIGMAR1 | |
| SCHEMBL28916127 | 0.84 | TRPA1 (0.57) | TRPA1CYP2D6SLC6A2TAAR1SIGMAR1 | |
| SCHEMBL9242001 | 0.76 | TRPA1 (0.62) | TRPA1ACECYP2D6SLC6A2TAAR1 | |
| SCHEMBL1889290 | 0.75 | TRPA1 (0.70) | TRPA1CYP2D6SLC6A2TAAR1SIGMAR1 | |
| SCHEMBL345523 | 0.73 | TRPA1 (0.55) | TRPA1SLC6A2TAAR1SIGMAR1MAOA | |
| SCHEMBL2604925 | 0.73 | TRPA1 (0.55) | TRPA1SLC6A2TAAR1SIGMAR1MAOA | |
| Alcohol SCHEMBL6562414 | 0.72 | TRPA1 (0.79) | TRPA1CYP2D6SLC6A2TAAR1SIGMAR1 | |
| SCHEMBL21306741 | 0.72 | TRPA1 (0.67) | TRPA1ACECYP2D6SLC6A2TAAR1 | |
| SCHEMBL27755423 | 0.71 | TRPA1 (0.51) | TRPA1ACECYP2D6SLC6A2TAAR1 | |
| SCHEMBL15101101 | 0.70 | TRPA1 (1.00) | TRPA1CYP2D6SLC6A2TAAR1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101657424-B | Dual-action antihypertensive agent | THERAVANCE INC US | 2014-09-24 | — | — | CN | disclosed |
| CN-101657424-A | Dual-action antihypertensive agent | THERAVANCE INC US | 2010-02-24 | — | — | CN | disclosed |