Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3123281 | 0.85 | TRPA1 (0.67) | TRPA1CYP2D6TAAR1SIGMAR1SLC6A2 | |
| SCHEMBL16202807 | 0.85 | TRPA1 (0.67) | TRPA1CYP2D6TAAR1SIGMAR1SLC6A2 | |
| SCHEMBL3123290 | 0.85 | TRPA1 (0.67) | TRPA1CYP2D6TAAR1SIGMAR1SLC6A2 | |
| SCHEMBL17418354 | 0.84 | TRPA1 (0.58) | TRPA1TAAR1SIGMAR1SLC6A2MAOA | |
| SCHEMBL10338651 | 0.84 | TRPA1 (0.58) | TRPA1TAAR1SIGMAR1SLC6A2MAOA | |
| SCHEMBL4437952 | 0.83 | TRPA1 (0.59) | TRPA1CYP2D6TAAR1SIGMAR1SLC6A2 | |
| SCHEMBL15101101 | 0.83 | TRPA1 (1.00) | TRPA1CYP2D6TAAR1SIGMAR1SLC6A2 | |
| SCHEMBL26456001 | 0.82 | TRPA1 (0.53) | TRPA1CYP2D6TAAR1SIGMAR1SLC6A2 | |
| SCHEMBL30468830 | 0.82 | TAAR1 (0.53) | TRPA1CYP2D6TAAR1SLC6A2SLC6A3 | |
| SCHEMBL9242001 | 0.81 | TRPA1 (0.62) | TRPA1CYP2D6TAAR1SIGMAR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288613-B2 | Lignan hydroxylase | SUNTORY HOLDINGS LIMITED (JP) | 2012-10-16 | — | — | US | disclosed |
| US-20110104360-A1 | LIGNAN HYDROXYLASE | SUNTORY HOLDINGS LIMITED (JP) | 2011-05-05 | — | — | US | disclosed |
| EP-2246418-A1 | LIGNAN HYDROXYLASE | Suntory Holdings Limited (JP) | 2010-11-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110104360-A1 | LIGNAN HYDROXYLASE | HPD, DNPH1, RNGTT | TRPA1 3137/4885CYP2D6 294/4885TAAR1 3221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.