Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 6/20 | 0.58 |
| ▸ | CA9 | Q16790 | 7/20 | 0.57 |
| ▸ | CA12 | O43570 | 6/20 | 0.57 |
| ▸ | CA1 | P00915 | 6/20 | 0.57 |
| ▸ | CA7 | P43166 | 6/20 | 0.57 |
| ▸ | CA13 | Q8N1Q1 | 6/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16283613 | 0.79 | MET (0.57) | MCL1CA9CA12CA1CA7 | |
| SCHEMBL9006756 | 0.78 | MCL1 (0.40) | MCL1CA9CA12CA1CA7 | |
| SCHEMBL3362853 | 0.77 | MAOB (0.59) | MCL1CA9CA12CA1CA7 | |
| SCHEMBL28372652 | 0.76 | MAOA (0.73) | MCL1CA9CA12CA1CA7 | |
| SCHEMBL31169352 | 0.74 | MCL1 (1.00) | MCL1CA9CA12CA1CA7 | |
| SCHEMBL5085582 | 0.74 | MCL1 (1.00) | MCL1CA9CA12CA1CA7 | |
| SCHEMBL5794191 | 0.72 | CA12 (1.00) | CA9CA12CA1CA7CA13 | |
| SCHEMBL27718011 | 0.72 | CA9 (0.57) | MCL1CA9CA12CA1CA7 | |
| SCHEMBL8442563 | 0.72 | HPGD (0.72) | MCL1KDM4EALDH1A1MAPTHPGD | |
| Fraxetin SCHEMBL43472 | 0.71 | CA9 (1.00) | MCL1CA9CA12CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101664463-B | Hypoglycemic active part and hypoglycemic effective component of luculia pinceana, preparation method and application thereof | UNIV HENAN | 2012-07-25 | — | — | CN | claimed |
| CN-101664463-A | Hypoglycemic active part and hypoglycemic effective component of luculia pinceana, preparation method and application thereof | UNIV HENAN | 2010-03-10 | — | — | CN | claimed |
| CN-101664463-B | Hypoglycemic active part and hypoglycemic effective component of luculia pinceana, preparation method and application thereof | UNIV HENAN | 2012-07-25 | — | — | CN | disclosed |
| CN-101664463-A | Hypoglycemic active part and hypoglycemic effective component of luculia pinceana, preparation method and application thereof | UNIV HENAN | 2010-03-10 | — | — | CN | disclosed |