Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 1.00 |
| ▸ | CA1 | P00915 | 3/20 | 1.00 |
| ▸ | CA7 | P43166 | 3/20 | 1.00 |
| ▸ | CA9 | Q16790 | 3/20 | 1.00 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 1.00 |
| ▸ | CA2 | P00918 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15266240 | 0.81 | CA9 (0.69) | CA12CA1CA7CA9CA13 | |
| SCHEMBL28372652 | 0.79 | MAOA (0.73) | CA12CA1CA7CA9CA13 | |
| SCHEMBL17047859 | 0.78 | ALDH1A1 (0.70) | CA12CA1CA7CA9CA13 | |
| SCHEMBL4772250 | 0.77 | KDM4E (0.74) | CA12CA1CA7CA9CA13 | |
| 5,6,7-Trimethoxycoumarin SCHEMBL4743900 | 0.76 | ALDH1A1 (0.62) | CA12CA1CA7CA9CA13 | |
| Fraxidin Methyl Ether SCHEMBL2464275 | 0.76 | CA9 (1.00) | CA12CA1CA7CA9CA13 | |
| SCHEMBL3362753 | 0.75 | CA9 (0.70) | CA12CA1CA7CA9CA13 | |
| Isobergaptene SCHEMBL2253427 | 0.74 | CYP3A4 (1.00) | CA12CA1CA7CA9CA13 | |
| Bergapten SCHEMBL15534211 | 0.73 | ALDH1A1 (0.82) | CA12CA1CA7CA9CA13 | |
| SCHEMBL15263865 | 0.73 | CA12 (0.57) | CA12CA1CA7CA9CA13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113831313-B | Preparation method and application of high-purity coumarin derivative | 山东省分析测试中心 | 2023-05-05 | — | — | CN | claimed |
| CN-113831313-A | Preparation method and application of high-purity coumarin derivative | 山东省分析测试中心 | 2021-12-24 | — | — | CN | claimed |
| CN-113831313-B | Preparation method and application of high-purity coumarin derivative | 山东省分析测试中心 | 2023-05-05 | — | — | CN | disclosed |
| CN-113831313-A | Preparation method and application of high-purity coumarin derivative | 山东省分析测试中心 | 2021-12-24 | — | — | CN | disclosed |
| WO-2006026853-A1 | PRICKLY ASH PREPARATIONS AND USES THEREOF AS ANTIVIRAL AGENTS | BIONICHE LIFE SCIENCES INC. (CA) | 2006-03-16 | — | — | WO | disclosed |