Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Tetrabuthylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 3/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | TACR2 | P21452 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabuthylammonium SCHEMBL623145 | 0.98 | SLC22A1 (0.52) | SLC22A1CA12CA1CA2GLA | |
| Tetrabuthylammonium SCHEMBL28976384 | 0.98 | SLC22A1 (0.52) | SLC22A1CA12CA1CA2GLA | |
| Tetrabuthylammonium SCHEMBL28252771 | 0.98 | SLC22A1 (0.52) | SLC22A1CA12CA1CA2GLA | |
| Tetrabuthylammonium SCHEMBL27681043 | 0.96 | SLC22A1 (0.50) | SLC22A1CA12CA1CA2GLA | |
| Tetrabuthylammonium SCHEMBL28387135 | 0.96 | SLC22A1 (0.50) | SLC22A1CA12CA1CA2GLA | |
| Tetrabuthylammonium SCHEMBL8432647 | 0.90 | SLC22A1 (0.44) | SLC22A1CA12CA1CA2GLA | |
| Tetrabuthylammonium SCHEMBL22089637 | 0.89 | SLC22A1 (0.43) | SLC22A1CA12CA1CA2GLA | |
| Tetrabuthylammonium SCHEMBL27564352 | 0.89 | SLC22A1 (0.43) | SLC22A1CA12CA1CA2GLA | |
| Tetrabuthylammonium SCHEMBL8432649 | 0.89 | SLC22A1 (0.43) | SLC22A1CA12CA1CA2GLA | |
| Phenol SCHEMBL28185432 | 0.87 | CA12 (0.61) | CA12CA1CA2GLACA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101663620-A | Low etch cleaning composition for removing resist | ANJI MICROELECTRONICS SHANGHAI | 2010-03-03 | — | — | CN | disclosed |