Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 5/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | AGXT | P21549 | 2/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL2782130 | 0.98 | PSMD14 (0.43) | PSMD14HSP90AA1MMP2MC4RRAD52 | |
| Trifluoromethanesulfonic Acid SCHEMBL4894043 | 0.83 | ACHE (0.37) | PSMD14HSP90AA1MMP2MC4RRAD52 | |
| SCHEMBL7774985 | 0.77 | KDM4E (0.54) | PSMD14HSP90AA1MMP2MC4RRAD52 | |
| SCHEMBL2479791 | 0.73 | PSMD14 (0.47) | PSMD14HSP90AA1MMP2MC4RRAD52 | |
| SCHEMBL26358245 | 0.71 | PSMD14 (0.55) | PSMD14HSP90AA1MMP2MC4RRAD52 | |
| SCHEMBL15807068 | 0.71 | PSMD14 (0.50) | PSMD14HSP90AA1MMP2MC4RRAD52 | |
| SCHEMBL776074 | 0.67 | LMNA (0.58) | IDO1LOXL2TAAR1LMNAAGXT | |
| SCHEMBL777661 | 0.64 | IDO1 (0.47) | IDO1LOXL2TAAR1LMNAAGXT | |
| SCHEMBL19349171 | 0.64 | TAAR1 (0.50) | IDO1LOXL2TAAR1LMNAAOC3 | |
| SCHEMBL131869 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534667-B1 | MUSCARINIC AGONISTS | LILLY CO ELI (US) | 2010-12-15 | — | — | EP | disclosed |
| CN-1556788-A | Muscarinic agonists | — | 2004-12-22 | — | — | CN | disclosed |