Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | CES2 | O00748 | 9/20 | 0.52 |
| ▸ | CES1 | P23141 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27864542 | 0.85 | MAPT (0.65) | MAPTALDH1A1CES2CES1LMNA | |
| SCHEMBL4094781 | 0.82 | CES2 (0.62) | MAPTALDH1A1CES2CES1LMNA | |
| SCHEMBL4826427 | 0.82 | CES2 (0.68) | MAPTALDH1A1CES2CES1LMNA | |
| SCHEMBL9578949 | 0.82 | MAPT (0.66) | MAPTALDH1A1CES2CES1LMNA | |
| SCHEMBL27957931 | 0.80 | CES2 (0.59) | MAPTALDH1A1CES2CES1LMNA | |
| SCHEMBL8460124 | 0.80 | MAPT (0.59) | MAPTALDH1A1CES2CES1LMNA | |
| SCHEMBL22407126 | 0.80 | MAPT (0.59) | MAPTALDH1A1CES2CES1LMNA | |
| Bromide SCHEMBL9419968 | 0.80 | CES2 (0.65) | MAPTALDH1A1CES2CES1LMNA | |
| SCHEMBL5132603 | 0.78 | TDP1 (0.56) | MAPTALDH1A1CES2CES1LMNA | |
| SCHEMBL491263 | 0.78 | CES2 (0.62) | MAPTALDH1A1CES2CES1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106581747-A | Strontium-containing bone cement and preparation method | 山东明德生物医学工程有限公司 | 2017-04-26 | — | — | CN | disclosed |
| CN-101888835-A | Coating suitable for medicament contact | VALSPAR SOURCING INC | 2010-11-17 | — | — | CN | disclosed |