Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 8/20 | 0.68 |
| ▸ | CES1 | P23141 | 7/20 | 0.68 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | XBP1 | P17861 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 2/20 | 0.52 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9419968 | 0.97 | CES2 (0.65) | CES2CES1MAPTALDH1A1LMNA | |
| SCHEMBL491263 | 0.90 | CES2 (0.62) | CES2CES1MAPTALDH1A1LMNA | |
| SCHEMBL8120050 | 0.87 | CES2 (0.59) | CES2CES1MAPTALDH1A1LMNA | |
| SCHEMBL3101206 | 0.85 | CES2 (0.56) | CES2CES1MAPTALDH1A1LMNA | |
| SCHEMBL14886367 | 0.85 | CES2 (0.67) | CES2CES1MAPTALDH1A1LMNA | |
| SCHEMBL9861745 | 0.84 | CES2 (0.54) | CES2CES1MAPTALDH1A1LMNA | |
| SCHEMBL27864542 | 0.84 | MAPT (0.65) | CES2CES1MAPTALDH1A1LMNA | |
| Lithium Ion SCHEMBL8120046 | 0.84 | CES2 (0.54) | CES2CES1MAPTALDH1A1LMNA | |
| SCHEMBL45539 | 0.83 | CES2 (0.68) | CES2CES1MAPTALDH1A1LMNA | |
| Benzil SCHEMBL8382614 | 0.82 | CES2 (0.88) | CES2CES1MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250486-A | Catalyst comprising a manganese compound, a chelate compound, a base and an unsaturated ketone or ether; controlled molecular weight; odorless; stabile thermal properties when blended with styrene resins | GENERAL ELECTRIC COMPANY (US) | 1993-10-05 | — | — | US | claimed |
| CN-1018179-B | HYDROLYSIS OF ACTIVATED OLEFINIC KETONES AND ALDEHYDES | FRIES & FRIES INC (US) | 1992-09-09 | — | — | CN | claimed |
| EP-0491190-A2 | Polyphenylene ether process and resin composition | GENERAL ELECTRIC COMPANY (US) | 1992-06-24 | — | — | EP | claimed |
| US-5037943-A | Oxidative coupling using alkaline catalysts system of manganese chelate and unsaturated or diketune or vinyl ether | GENERAL ELECTRIC CO. (US) | 1991-08-06 | — | — | US | claimed |
| US-4070259-A | DIELS-ALDER REACTION PRODUCT, PAINTS, VARNISHES, INKS | U C B, SOCIETE ANONYME (BE) | 1978-01-24 | — | — | US | claimed |
| JP-2281013-A | — | — | None | — | — | JP | disclosed |
| US-20200223779-A1 | CATALYTIC CYCLE FOR PRODUCTION OF 1,1-DISUBSTITUTED ALKENES | SIRRUS, INC. | 2020-07-16 | — | — | US | disclosed |
| WO-2019060188-A1 | CATALYTIC CYCLE FOR PRODUCTION OF 1,1-DISUBSTITUTED ALKENES | SIRRUS, INC. (US) | 2019-03-28 | — | — | WO | disclosed |
| EP-2768897-B1 | METHODS FOR MAKING METHYLENE BETA-DIKETONE MONOMERS | SIRRUS INC (US) | 2019-01-23 | — | — | EP | disclosed |
| EP-3339301-A2 | METHODS FOR MAKING METHYLENE BETA-DIKETONE MONOMERS | Sirrus, Inc. (US) | 2018-06-27 | — | — | EP | disclosed |
| US-20170342011-A1 | METHYLENE BETA-DIKETONE MONOMERS, METHODS FOR MAKING METHYLENE BETA-DIKETONE MONOMERS, POLYMERIZABLE COMPOSITIONS AND PRODUCTS FORMED THEREFROM | SIRRUS, INC. | 2017-11-30 | — | — | US | disclosed |
| US-20170342011-A1 | METHYLENE BETA-DIKETONE MONOMERS, METHODS FOR MAKING METHYLENE BETA-DIKETONE MONOMERS, POLYMERIZABLE COMPOSITIONS AND PRODUCTS FORMED THEREFROM | SIRRUS, INC. | 2017-11-30 | — | — | US | disclosed |
| JP-H02281013-A | DIKETONE COMPOUND COPOLYMER | CEMEDINE CO LTD | 1990-11-16 | — | — | JP | disclosed |
| EP-0026519-B1 | PHOTOGRAPHIC SILVER HALIDE EMULSION MATERIAL CONTAINING AN ANTIFOGGANT PRECURSOR | AGFA-GEVAERT N.V. (BE) | 1983-08-17 | — | — | EP | disclosed |
| US-4307175-A | Photographic silver halide emulsion material containing an antifoggant precursor | AGFA-GEVAERT, N.V. (BE) | 1981-12-22 | — | — | US | disclosed |
| EP-0026519-A1 | Photographic silver halide emulsion material containing an antifoggant precursor | AGFA-GEVAERT N.V. (BE) | 1981-04-08 | — | — | EP | disclosed |
| US-4154707-A | VINYLENEDICARBONYL COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-05-15 | — | — | US | disclosed |
| US-4105014-A | ACIDS AND BASES, EXOTHERMIC ISOMERIZATION | BATTELLE DEVELOPMENT CORPORATION (US) | 1978-08-08 | — | — | US | disclosed |
| US-4070259-A | DIELS-ALDER REACTION PRODUCT, PAINTS, VARNISHES, INKS | U C B, SOCIETE ANONYME (BE) | 1978-01-24 | — | — | US | disclosed |
| US-4004572-A | Solar energy collection and retrieval employing reversible photochemical isomerization | BATTELLE DEVELOPMENT CORPORATION (US) | 1977-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200223779-A1 | CATALYTIC CYCLE FOR PRODUCTION OF 1,1-DISUBSTITUTED ALKENES | ME1, ME3, ME2 | CES2 473/4885CES1 101/4885MAPT 3579/4885 |
| US-20170342011-A1 | METHYLENE BETA-DIKETONE MONOMERS, METHODS FOR MAKING METHYLENE BETA-DIKETONE MONOMERS, POLYMERIZABLE COMPOSITIONS AND PRODUCTS FORMED THEREFROM | B2M, BHMT2, ILK | CES2 3604/4885CES1 2860/4885MAPT 672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.