Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 15/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27774916 | 0.89 | REN (0.47) | RENKCNH2CNR1CNR2 | |
| SCHEMBL27795804 | 0.83 | REN (0.48) | RENKCNH2CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL2806393 | 0.73 | REN (0.53) | RENKCNH2CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL27774915 | 0.72 | REN (0.53) | RENKCNH2 | |
| SCHEMBL27774898 | 0.67 | ENPP2 (0.34) | REN | |
| SCHEMBL13131567 | 0.66 | REN (0.83) | RENKCNH2 | |
| SCHEMBL13132570 | 0.66 | REN (0.56) | RENKCNH2 | |
| SCHEMBL27795797 | 0.66 | SLC22A12 (0.38) | RENCNR1CNR2 | |
| SCHEMBL13131359 | 0.64 | CNR1 (0.47) | RENCNR1CNR2L3MBTL1 | |
| SCHEMBL13132365 | 0.64 | CNR1 (0.41) | RENCNR1CNR2SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679324-B | Morpholine derivatives | MITSUBISHI TANABE PHARMA CORP | 2012-10-03 | — | — | CN | disclosed |
| CN-101679324-A | Morpholine derivatives | MITSUBISHI TANABE PHARMA CORP | 2010-03-24 | — | — | CN | disclosed |