Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | REN | P00797 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27774894 | 0.85 | KDM1A (0.36) | ENPP2GHSRNR1H4MAPTHPGD | |
| SCHEMBL27795797 | 0.83 | SLC22A12 (0.38) | GHSRMAPTHPGDTSHRREN | |
| SCHEMBL27795799 | 0.70 | TSHR (0.43) | NR1H4MAPTHPGDTSHRREN | |
| SCHEMBL27795803 | 0.68 | KDM4E (0.41) | MAPTHPGD | |
| SCHEMBL27795796 | 0.67 | SLC22A12 (0.38) | NR1H4REN | |
| SCHEMBL27795806 | 0.67 | REN (0.43) | REN | |
| SCHEMBL27774916 | 0.65 | REN (0.47) | REN | |
| Hydrochloric Acid SCHEMBL27774966 | 0.65 | TSHR (0.47) | MAPTHPGDTSHR | |
| SCHEMBL27774920 | 0.64 | KDM4E (0.47) | MAPTHPGDTSHR | |
| SCHEMBL13132300 | 0.62 | REN (0.40) | NR1H4REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679324-B | Morpholine derivatives | MITSUBISHI TANABE PHARMA CORP | 2012-10-03 | — | — | CN | disclosed |
| CN-101679324-A | Morpholine derivatives | MITSUBISHI TANABE PHARMA CORP | 2010-03-24 | — | — | CN | disclosed |