Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL88762 | 0.81 | NCF1 (0.52) | NCF1ACP1 | |
| SCHEMBL30065410 | 0.81 | HPGD (0.64) | HPGDKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL396614 | 0.81 | HPGD (0.64) | HPGDKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL89580 | 0.80 | NCF1 (0.49) | NCF1HPGDLMNASMN1; SMN2ALOX15 | |
| SCHEMBL89579 | 0.80 | NCF1 (0.49) | NCF1HPGDLMNASMN1; SMN2MEN1 | |
| SCHEMBL28611035 | 0.79 | HPGD (0.62) | HPGDKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4270484 | 0.79 | NCF1 (0.56) | NCF1HPGDKDM4EALDH1A1LMNA | |
| SCHEMBL4270523 | 0.77 | NCF1 (0.54) | NCF1 | |
| SCHEMBL90018 | 0.77 | ALOX15 (0.53) | NCF1HPGDKDM4EALDH1A1ALOX15 | |
| SCHEMBL8264291 | 0.77 | LTB4R (0.49) | NCF1HPGDKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679324-B | Morpholine derivatives | MITSUBISHI TANABE PHARMA CORP | 2012-10-03 | — | — | CN | disclosed |
| CN-101679324-A | Morpholine derivatives | MITSUBISHI TANABE PHARMA CORP | 2010-03-24 | — | — | CN | disclosed |