Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.56 |
| ▸ | MMP2 | P08253 | 2/20 | 0.56 |
| ▸ | MMP9 | P14780 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.49 |
| ▸ | ESRRG | P62508 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Resorcinol SCHEMBL27796353 | 0.87 | MAOA (0.53) | MMP1MMP2MMP9MEN1KMT2A | |
| SCHEMBL28749872 | 0.87 | KMT2A (0.63) | MEN1KMT2ATAAR1CA12CA1 | |
| SCHEMBL31078919 | 0.82 | BAZ1A (0.69) | MMP1MMP2MMP9MEN1KMT2A | |
| SCHEMBL27695098 | 0.79 | CNR1 (0.57) | MEN1KMT2AMAPTKDM4ENPC1 | |
| SCHEMBL10804897 | 0.74 | MEN1 (0.81) | MEN1KMT2AESRRGKDM4ENPC1 | |
| SCHEMBL18031165 | 0.74 | MAOA (0.67) | MMP1MMP2MMP9MEN1KMT2A | |
| SCHEMBL27599974 | 0.74 | SMN1; SMN2 (0.67) | MEN1KMT2ATAAR1MAPTKDM4E | |
| SCHEMBL3070329 | 0.73 | KMT2A (0.76) | MEN1KMT2ATAAR1CA12CA1 | |
| SCHEMBL17151476 | 0.73 | KMT2A (0.59) | MEN1KMT2ATAAR1CA12CA1 | |
| SCHEMBL2267263 | 0.72 | CA12 (0.57) | MMP1MMP2MMP9MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101880246-A | Substituted benzoyl urea compound and preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2010-11-10 | — | — | CN | claimed |
| CN-101880246-B | Substituted benzoyl urea compound and preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2012-10-03 | — | — | CN | disclosed |
| CN-101880246-A | Substituted benzoyl urea compound and preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2010-11-10 | — | — | CN | disclosed |