Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | CDK9 | P50750 | 1/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.52 |
| ▸ | MMP1 | P03956 | 2/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
| ▸ | MMP9 | P14780 | 2/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27599974 | 0.88 | SMN1; SMN2 (0.67) | MAOAMAOBTSHRTP53SMN1; SMN2 | |
| Resorcinol SCHEMBL27796366 | 0.87 | MMP1 (0.56) | HIF1ATP53SMN1; SMN2MMP1MMP2 | |
| SCHEMBL7098404 | 0.80 | TP53 (0.68) | MAOAMAOBHIF1ATSHRTP53 | |
| Resorcinol SCHEMBL27796347 | 0.76 | HDAC1 (0.49) | SMN1; SMN2MMP1MMP2MMP9KMT2A | |
| SCHEMBL27582568 | 0.76 | MITF (0.58) | SMN1; SMN2EPHX2KMT2AMEN1NPC1 | |
| SCHEMBL11431155 | 0.76 | MAOA (0.56) | MAOAMAOBHIF1ATSHRTP53 | |
| SCHEMBL27582490 | 0.75 | KMT2A (0.73) | TSHRTP53SMN1; SMN2EPHX1EPHX2 | |
| SCHEMBL9400341 | 0.74 | ALDH1A1 (0.70) | MAOAMAOBHIF1ATSHRTP53 | |
| SCHEMBL27582561 | 0.73 | TGM2 (0.59) | SMN1; SMN2EPHX1EPHX2KMT2AMEN1 | |
| SCHEMBL27582545 | 0.73 | KMT2A (0.68) | TSHRTP53KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101880246-A | Substituted benzoyl urea compound and preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2010-11-10 | — | — | CN | claimed |
| CN-101880246-B | Substituted benzoyl urea compound and preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2012-10-03 | — | — | CN | disclosed |
| CN-101880246-A | Substituted benzoyl urea compound and preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2010-11-10 | — | — | CN | disclosed |