Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5649920 | 0.75 | KMT2A (0.40) | KMT2APKMHKDC1L3MBTL1ALDH1A1 | |
| SCHEMBL5652751 | 0.75 | LMNA (0.34) | KMT2APKMHKDC1L3MBTL1ALDH1A1 | |
| SCHEMBL5649654 | 0.73 | ALDH1A1 (0.44) | KMT2AALDH1A1MAPT | |
| SCHEMBL5647917 | 0.72 | ALOX5 (0.41) | KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL5651227 | 0.71 | ALDH1A1 (0.47) | KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL5650705 | 0.71 | KMT2A (0.43) | KMT2APKMHKDC1L3MBTL1ALDH1A1 | |
| SCHEMBL5648743 | 0.71 | IKBKB (0.40) | KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL5654089 | 0.70 | KMT2A (0.38) | KMT2APKMHKDC1L3MBTL1ALDH1A1 | |
| SCHEMBL5648881 | 0.70 | KMT2A (0.37) | KMT2APKMHKDC1L3MBTL1ALDH1A1 | |
| SCHEMBL5649021 | 0.70 | KMT2A (0.39) | KMT2APKMHKDC1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7795256-B2 | Thieno-pyridinone derivatives as kinase inhibitors | UCB PHARMA S.A. (BE) | 2010-09-14 | — | — | US | claimed |
| US-20070078131-A1 | Thieno-pyridinone derivatives as kinase inhibitors | CELLTECH R&D LIMITED (GB) | 2007-04-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078131-A1 | Thieno-pyridinone derivatives as kinase inhibitors | MAP3K6, MAP4K2, MAP3K15 | KMT2A 2311/4885PKM 300/4885HKDC1 1592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.