Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27776487 | 0.88 | MAPT (0.39) | FADS1MAPTHSD17B10KDM4EGRIN1 | |
| SCHEMBL27797335 | 0.84 | MAPT (0.52) | MAPTKDM4ETDP1AGTR1AGTR2 | |
| SCHEMBL4178486 | 0.77 | FADS1 (0.40) | FADS1HSD17B10 | |
| SCHEMBL3959525 | 0.76 | HDAC1 (0.39) | FADS1MAPTPDE4APDE4BPDE4C | |
| SCHEMBL3955467 | 0.68 | AXL (0.37) | FADS1CYP11B1CYP11B2 | |
| SCHEMBL3955475 | 0.68 | AXL (0.37) | FADS1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL5128633 | 0.67 | AXL (0.36) | FADS1CYP11B1CYP11B2 | |
| SCHEMBL27776485 | 0.65 | MAPT (0.50) | MAPTKDM4ETDP1AGTR1AGTR2 | |
| SCHEMBL3958309 | 0.64 | TSPO (0.47) | FADS1MAPTPDE4DHSD17B10KDM4E | |
| SCHEMBL3963515 | 0.63 | MAPT (0.47) | MAPTPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101636398-A | Pyridopyrimidinone compounds useful in treating sodium channel-mediated diseases or conditions | XENON PHARMACEUTICALS INC | 2010-01-27 | — | — | CN | disclosed |