SCHEMBL27797458

SCHEMBL27797458

Oc1ccc(C2CC(c3ccccc3)c3ccccc32)cc1

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.46
HTR2A P28223 1/20 0.42
HTR2C P28335 1/20 0.42
HTR2B P41595 1/20 0.42
HRH3 Q9Y5N1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1388099 0.87 SIGMAR1 (0.55) SIGMAR1HTR2AHTR2CHTR2BHRH3
SCHEMBL8527042 0.82 ESR2 (0.40)
SCHEMBL5709410 0.78 SIGMAR1 (0.48) SIGMAR1HTR2AHTR2CHTR2BHRH3
SCHEMBL13051102 0.78 SIGMAR1 (0.48) SIGMAR1HTR2AHTR2CHTR2BHRH3
SCHEMBL13906155 0.78 SIGMAR1 (0.48) SIGMAR1HTR2AHTR2CHTR2BHRH3
SCHEMBL28040971 0.78 SIGMAR1 (0.48) SIGMAR1HTR2AHTR2CHTR2BHRH3
SCHEMBL9134151 0.76 KDM1A (0.52) HTR2C
SCHEMBL9134150 0.76 KDM1A (0.52) HTR2C
SCHEMBL14804298 0.74 HTR2A (0.54) HTR2AHTR2CHTR2BHRH3
SCHEMBL4060712 0.72 SIGMAR1 (0.56) SIGMAR1HTR2AHTR2CHTR2BHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-220818346-U Industrial production system of 1, 1-di (4-hydroxyphenyl) -3-phenylindane 江苏鸣翔化工有限公司 2024-04-19 CN claimed
CN-220818346-U Industrial production system of 1, 1-di (4-hydroxyphenyl) -3-phenylindane 江苏鸣翔化工有限公司 2024-04-19 CN disclosed
CN-220818346-U Industrial production system of 1, 1-di (4-hydroxyphenyl) -3-phenylindane 江苏鸣翔化工有限公司 2024-04-19 CN disclosed
CN-220818346-U Industrial production system of 1, 1-di (4-hydroxyphenyl) -3-phenylindane 江苏鸣翔化工有限公司 2024-04-19 CN disclosed
CN-220257207-U Dehydration dehydrogenation adaptation crystallization reaction kettle 江苏鸣翔化工有限公司 2023-12-29 CN disclosed
CN-109804310-B Negative photosensitive resin composition, cured film, element and display device provided with cured film, and method for producing same 东丽株式会社 2022-09-30 CN disclosed
CN-114460809-A Negative photosensitive resin composition, cured film, display device provided with cured film, and method for producing same 东丽株式会社 2022-05-10 CN disclosed
CN-108885399-B Negative photosensitive resin composition, cured film, display device provided with cured film, and method for producing same 东丽株式会社 2022-03-15 CN disclosed
CN-108027561-B Negative photosensitive resin composition, cured film, element and display device provided with cured film, and method for producing same 东丽株式会社 2021-10-08 CN disclosed
CN-108027561-A Negative light-sensitive resin combination, cured film, the element for possessing cured film and display device and its manufacture method 东丽株式会社 2018-05-11 CN disclosed
CN-101622236-A Novel epoxy compound, alkali-developable resin composition, and alkali-developable photosensitive resin composition ADEKA CORP 2010-01-06 CN disclosed