Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3434137 | 0.79 | TSHR (0.48) | TSHRTACR1IDO1PTPN1AGXT | |
| SCHEMBL872392 | 0.78 | ALDH1A1 (0.39) | TSHRKDM4ETACR1IDO1PTPN1 | |
| SCHEMBL18640775 | 0.76 | TSHR (0.56) | TSHRKDM4EPOLBTACR1IDO1 | |
| SCHEMBL10202767 | 0.76 | TSHR (0.44) | TSHRTACR1IDO1PTPN1AGXT | |
| SCHEMBL1065786 | 0.76 | TSHR (0.44) | TSHRTACR1IDO1PTPN1AGXT | |
| SCHEMBL10940340 | 0.74 | TSHR (0.52) | TSHRIDO1AGXTALDH1A1SLC6A2 | |
| SCHEMBL726130 | 0.74 | TSHR (0.52) | TSHRIDO1AGXTALDH1A1SLC6A2 | |
| SCHEMBL5016440 | 0.74 | TSHR (0.52) | TSHRIDO1AGXTALDH1A1SLC6A2 | |
| SCHEMBL11625744 | 0.74 | TSHR (0.52) | TSHRIDO1AGXTALDH1A1SLC6A2 | |
| SCHEMBL267071 | 0.74 | TSHR (0.52) | TSHRKDM4EPOLBIDO1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155806-A1 | PHOSPHAZENE HYDROGELS WITH CHEMICAL CORSS -LINK, PREPARATION METHOD THEREOF AND USE THEREOF | Korea Institute of Science and Technology (KR) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008153278-A1 | PHOSPHAZENE HYDROGELS WITH CHEMICAL CORSS -LINK, PREPARATION METHOD THEREOF AND USE THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2008-12-18 | — | — | WO | disclosed |