SCHEMBL872392

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2779795	0.78	TSHR (0.46)	ALDH1A1TDP1KDM4ETSHRPTPN1
	SCHEMBL3434137	0.77	TSHR (0.48)	ALDH1A1TDP1TSHRPTPN1IDO1
	SCHEMBL10202767	0.73	TSHR (0.44)	ALDH1A1TDP1TSHRPTPN1IDO1
	SCHEMBL1065786	0.73	TSHR (0.44)	ALDH1A1TDP1TSHRPTPN1IDO1
	SCHEMBL726130	0.72	TSHR (0.52)	ALDH1A1TDP1TSHRIDO1AGXT
	SCHEMBL10940340	0.72	TSHR (0.52)	ALDH1A1TDP1TSHRIDO1AGXT
	SCHEMBL11625744	0.72	TSHR (0.52)	ALDH1A1TDP1TSHRIDO1AGXT
	SCHEMBL5016440	0.72	TSHR (0.52)	ALDH1A1TDP1TSHRIDO1AGXT
	SCHEMBL267071	0.72	TSHR (0.52)	ALDH1A1TDP1KDM4ETSHRPTPN1
	SCHEMBL16886241	0.70	TSHR (0.41)	ALDH1A1TDP1TSHRPTPN1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.