Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 3/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2838101 | 0.90 | GAA (0.40) | ALOX5GAAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL2843497 | 0.81 | GPR35 (0.34) | GPR35MAPT | |
| SCHEMBL2843494 | 0.81 | GPR35 (0.34) | GPR35MAPT | |
| SCHEMBL2840941 | 0.80 | ALDH1A1 (0.33) | GAAGPR35MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL15681088 | 0.77 | GAA (0.38) | GAA | |
| SCHEMBL7346699 | 0.76 | ERN1 (0.36) | MAPT | |
| SCHEMBL14550752 | 0.73 | AKR1B1 (0.37) | GAAGPR35MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL7349533 | 0.71 | AKR1B1 (0.37) | GPR35MAPT | |
| SCHEMBL27798571 | 0.70 | EPHX2 (0.40) | GAANPC1RAB9A | |
| SCHEMBL7350240 | 0.70 | AKR1B1 (0.35) | GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101939313-B | 3,8-diaminotetrahydroquinoline derivative | ZERIA PHARM CO LTD | 2013-05-22 | — | — | CN | disclosed |
| CN-101939313-A | 3,8-diamino tetrahydroquinoline derivative | ZERIA PHARM CO LTD | 2011-01-05 | — | — | CN | disclosed |