Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 2/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.42 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMPD2 | O60906 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9150858 | 0.81 | PAM (0.60) | PAMLMNATDP1PDE5ATRIM24 | |
| SCHEMBL15540625 | 0.79 | PAM (0.58) | PAMLMNAKMT2AMEN1TDP1 | |
| SCHEMBL27285003 | 0.79 | PAM (0.58) | PAMKMT2AMEN1PDE5AALDH1A1 | |
| SCHEMBL15540628 | 0.79 | PAM (0.58) | PAMLMNAKMT2AMEN1TDP1 | |
| SCHEMBL8828323 | 0.79 | PAM (0.58) | PAMCYP2D6MAOBSMN1; SMN2 | |
| SCHEMBL8828328 | 0.79 | PAM (0.58) | PAMCYP2D6MAOBSMN1; SMN2 | |
| SCHEMBL28010950 | 0.79 | PAM (0.58) | PAMPTGDR2PDE5AALDH1A1CYP2D6 | |
| SCHEMBL30443677 | 0.79 | PAM (0.58) | PAMLMNAKMT2AMEN1TDP1 | |
| SCHEMBL22070597 | 0.78 | PAM (0.56) | PAMLMNATDP1PDE5AALDH1A1 | |
| SCHEMBL8844798 | 0.78 | SMPD2 (0.58) | PAMTDP1ALDH1A1CYP2D6HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101914023-B | Preparation method of optically pure 4-aryl-2-hydroxy-butyric ester | UNIV SHANGHAI JIAOTONG | 2013-05-22 | — | — | CN | disclosed |
| CN-101941900-A | Preparation method of optically pure 4-aryl-2-hydroxy-butyric acid | UNIV SHANGHAI JIAOTONG | 2011-01-12 | — | — | CN | disclosed |
| CN-101914023-A | Preparation method of optically pure 4-aryl-2-hydroxy-butyric ester | UNIV SHANGHAI JIAOTONG | 2010-12-15 | — | — | CN | disclosed |