Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | JUN | P05412 | 1/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CDK4 | P11802 | 1/20 | 0.50 |
| ▸ | CCND1 | P24385 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | GUSB | P08236 | 1/20 | 0.49 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6553851 | 0.86 | NFKB1 (0.57) | PAMNFKB1CA2CA1CA4 | |
| SCHEMBL11189506 | 0.86 | NFKB1 (0.57) | PAMNFKB1CA2CA1CA4 | |
| SCHEMBL9574440 | 0.81 | NFKB1 (0.55) | NFKB1CA2CA1CA4JUN | |
| SCHEMBL27799088 | 0.81 | PAM (0.60) | PAMNFKB1CA2CA1CA4 | |
| SCHEMBL15540628 | 0.79 | PAM (0.58) | PAMNFKB1TRPA1MAPTLMNA | |
| SCHEMBL30443677 | 0.79 | PAM (0.58) | PAMNFKB1TRPA1MAPTLMNA | |
| SCHEMBL8828328 | 0.79 | PAM (0.58) | PAMNFE2L2MAPTCYP1A1CYP1B1 | |
| SCHEMBL15540625 | 0.79 | PAM (0.58) | PAMNFKB1TRPA1MAPTLMNA | |
| SCHEMBL28010950 | 0.79 | PAM (0.58) | PAMNFKB1CA2CA1CA4 | |
| SCHEMBL8828323 | 0.79 | PAM (0.58) | PAMNFE2L2MAPTCYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5429935-A | Reduction of the corresponding ketone with microorganisms | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1995-07-04 | — | — | US | claimed |