Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.33 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.33 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.33 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.33 |
| ▸ | BCL9 | O00512 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7403186 | 0.80 | DRD1 (0.42) | HTR1ADRD2DRD1HTR2AALDH1A1 | |
| SCHEMBL27799150 | 0.72 | NLRP3 (0.41) | SRD5A1ALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL1993937 | 0.71 | KMT2A (0.43) | ALDH1A1KDM4EBCL9CTNNB1KMT2A | |
| SCHEMBL12930786 | 0.68 | ALDH1A1 (0.36) | ALDH1A1GAAKDM4EKMT2AALOX15 | |
| SCHEMBL3252645 | 0.67 | ALDH1A1 (0.43) | HTR1ADRD2DRD1HTR2AALDH1A1 | |
| SCHEMBL1997708 | 0.67 | KMT2A (0.45) | HTR1ADRD2DRD1HTR2AALDH1A1 | |
| SCHEMBL3586115 | 0.67 | PTGIR (0.40) | SRD5A1KDM4ENOTUM | |
| SCHEMBL1261118 | 0.67 | KDM4E (0.51) | ALDH1A1GAAKDM4EKMT2AALOX15 | |
| SCHEMBL27778144 | 0.66 | KMT2A (0.44) | HTR1ADRD2DRD1HTR2AALDH1A1 | |
| SCHEMBL13074756 | 0.66 | AKR1C3 (0.39) | SRD5A1NOTUMKMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101622241-B | Benzimidazole compound and medical application thereof | MITSUBISHI TANABE PHARMA CORP | 2013-05-22 | — | — | CN | disclosed |
| CN-101622241-A | Benzimidazole compound and medical application thereof | MITSUBISHI TANABE PHARMA CORP | 2010-01-06 | — | — | CN | disclosed |