Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | KYNU | Q16719 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27416181 | 0.81 | POLB (0.54) | KMT2APOLBL3MBTL1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL28146281 | 0.78 | ALDH1A1 (0.41) | KMT2AMAPK1L3MBTL1MAPTPTGS2 | |
| SCHEMBL16774994 | 0.75 | KMT2A (0.44) | KMT2APOLBMAPK1L3MBTL1MAPT | |
| SCHEMBL25591711 | 0.73 | ELANE (0.51) | KMT2APOLBMAPK1TDP1 | |
| SCHEMBL9906190 | 0.72 | TSHR (0.47) | KMT2APOLBMAPTALDH1A1KDM4E | |
| SCHEMBL10339568 | 0.72 | KMT2A (0.44) | KMT2APOLBMAPK1L3MBTL1MAPT | |
| SCHEMBL7735376 | 0.71 | KMT2A (0.53) | KMT2AL3MBTL1MAPTPTGS1PTGS2 | |
| SCHEMBL16453798 | 0.71 | KMT2A (0.53) | KMT2AL3MBTL1MAPTPTGS1PTGS2 | |
| SCHEMBL3236310 | 0.70 | KMT2A (0.56) | KMT2APTGS1PTGS2ALDH1A1TSHR | |
| SCHEMBL5544986 | 0.69 | KMT2A (0.67) | KMT2APOLBL3MBTL1PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679228-A | Novel 3-phenylacrylic acid derivatives as activators of receptors of the PPAR type, method for preparing same and use thereof in cosmetic or pharmaceutical compositions | JEAN-GUY BOITEAU | 2010-03-24 | — | — | CN | disclosed |