Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ESRRB | O95718 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16453798 | 1.00 | KMT2A (0.53) | KMT2ATSHRPTGS1PTGS2TDP1 | |
| SCHEMBL27697444 | 0.87 | KMT2A (0.49) | KMT2ATSHRPTGS1PTGS2TDP1 | |
| SCHEMBL1397470 | 0.83 | KMT2A (0.58) | KMT2ATSHRTDP1PGRADRA2A | |
| SCHEMBL8845741 | 0.82 | KMT2A (0.55) | KMT2ATSHRPTGS1PTGS2TDP1 | |
| SCHEMBL2097359 | 0.82 | KMT2A (0.55) | KMT2ATSHRPTGS1PTGS2TDP1 | |
| SCHEMBL10957360 | 0.81 | KMT2A (0.50) | KMT2ATSHRPTGS1PTGS2TDP1 | |
| SCHEMBL18082660 | 0.81 | PLK1 (0.56) | LMNASMN1; SMN2GAAALDH1A1HTT | |
| SCHEMBL8532948 | 0.81 | KMT2A (0.50) | KMT2ATSHRPTGS1PTGS2TDP1 | |
| SCHEMBL18770496 | 0.81 | KMT2A (0.50) | KMT2ATSHRPTGS1PTGS2TDP1 | |
| SCHEMBL5866532 | 0.81 | KMT2A (0.57) | KMT2ATSHRTDP1PGRADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410757-B1 | TAXANE COMPOUNDS | BIO RESEARCH CORPORATION OF YOKOHAMA (JP) | 2002-06-25 | — | — | US | claimed |
| CN-107522751-B | High-steric-hindrance chiral ferrocene P, N, N ligand, preparation method and application | 中国科学院大连化学物理研究所 | 2020-01-21 | — | — | CN | disclosed |
| CN-107522751-A | A kind of high steric-hindrance amino chiral ferrocene P, N, N part and preparation method and application | 中国科学院大连化学物理研究所 | 2017-12-29 | — | — | CN | disclosed |
| CN-102516202-B | N-fluoro-1, 1'-binaphthyl-2, 2'-sulfimide and preparation method thereof | UNIV TIANJIN | 2013-12-04 | — | — | CN | disclosed |
| CN-102516202-A | N-fluoro-1, 1'-binaphthyl-2, 2'-sulfimide and preparation method thereof | UNIV TIANJIN | 2012-06-27 | — | — | CN | disclosed |
| EP-2397504-A1 | (METH)ACRYLATE COMPOUND CONTAINING AROMATIC GROUP | Showa Denko K.K. (JP) | 2011-12-21 | — | — | EP | disclosed |
| US-20110294948-A1 | AROMATIC GROUP-CONTAINING (METH) ACRYLATE COMPOUND | SHOWA DENKO K.K. (JP) | 2011-12-01 | — | — | US | disclosed |
| CN-1090617-C | Pyrrole derivatives and pharmaceutical compositions | NIPPON SHINYAKU CO LTD (JP) | 2002-09-11 | — | — | CN | disclosed |
| CN-1349796-A | Pyrrole derivatives and medicine composition | NIPPON SHINYAKU CO LTD (JP) | 2002-05-22 | — | — | CN | disclosed |
| CN-1186485-A | Pyrrole derivatives and pharmaceutical compositions | NIPPON SHINYAKU CO LTD (JP) | 1998-07-01 | — | — | CN | disclosed |
| US-5200518-A | Reduced side effcts | KANGWEON NATIONAL UNIVERSITY (KR) | 1993-04-06 | — | — | US | disclosed |
| EP-0114059-B1 | METHOD OF PREPARING A POLYAMIDE ACID COMPOSITION FOR PREPARING POLYIMIDE | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-06-14 | — | — | EP | disclosed |
| US-4515915-A | Polyamide acid composition for preparing polyimide | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-05-07 | — | — | US | disclosed |
| EP-0114059-A2 | Method of preparing a polyamide acid composition for preparing polyimide | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1984-07-25 | — | — | EP | disclosed |
| EP-0045198-A2 | 1,1-Disubstituted carba-2-penems and their production | Takeda Chemical Industries, Ltd. (JP) | 1982-02-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294948-A1 | AROMATIC GROUP-CONTAINING (METH) ACRYLATE COMPOUND | ACR, MMAB, ATR | KMT2A 811/4885TSHR 1638/4885PTGS1 2157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.