Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28679013 | 0.84 | POLB (0.65) | POLBTSHRALDH1A1MEN1KMT2A | |
| SCHEMBL27799343 | 0.81 | KMT2A (0.50) | POLBTSHRALDH1A1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL28146281 | 0.75 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL24225368 | 0.75 | ELANE (0.49) | POLBTSHRALDH1A1MEN1KMT2A | |
| SCHEMBL11163913 | 0.73 | POLB (0.49) | POLBTSHRALDH1A1MEN1KMT2A | |
| SCHEMBL10440120 | 0.73 | PIN1 (0.44) | POLBTSHRALDH1A1MEN1KMT2A | |
| SCHEMBL13751893 | 0.73 | MMP8 (0.54) | POLBTSHRALDH1A1MEN1KMT2A | |
| SCHEMBL9126861 | 0.73 | MMP8 (0.54) | POLBTSHRALDH1A1MEN1KMT2A | |
| SCHEMBL9567088 | 0.73 | MEN1 (0.51) | POLBTSHRALDH1A1MEN1KMT2A | |
| SCHEMBL16477715 | 0.73 | MMP8 (0.54) | POLBTSHRALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1494906-A | Application of compound in preparation of medicine for preventing and curing multiple drug resistance | ��̩��˹ҩ��ɷ�����˾ | 2004-05-12 | — | — | CN | disclosed |
| CN-1086386-C | Multi-drug resistance modifiers | VERTEX PHARMA (US) | 2002-06-19 | — | — | CN | disclosed |