Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.59 |
| ▸ | KDM1A | O60341 | 2/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21088669 | 0.82 | KDM1A (0.58) | CTSKKDM1AHDAC3TNKSHDAC4 | |
| SCHEMBL21088859 | 0.82 | KDM1A (0.58) | CTSKKDM1AHDAC3TNKSHDAC4 | |
| SCHEMBL18172738 | 0.71 | KDM1A (0.56) | CTSKKDM1APOLBHDAC3TNKS | |
| SCHEMBL18172735 | 0.71 | KDM1A (0.56) | CTSKKDM1APOLBHDAC3TNKS | |
| SCHEMBL18173266 | 0.71 | KDM1A (0.56) | CTSKKDM1APOLBHDAC3TNKS | |
| SCHEMBL3795722 | 0.71 | CTSK (0.48) | CTSKKDM1APOLBALDH1A1LMNA | |
| SCHEMBL9149399 | 0.70 | KDM1A (0.50) | CTSKKDM1A | |
| SCHEMBL9146261 | 0.70 | KDM1A (0.50) | CTSKKDM1A | |
| SCHEMBL9149393 | 0.70 | KDM1A (0.50) | CTSKKDM1A | |
| SCHEMBL3323648 | 0.68 | KCNQ3 (0.54) | KDM1AHDAC4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679273-A | 1-substituted tetrahydroisoquinoline compound | ASTELLAS PHARMA INC | 2010-03-24 | — | — | CN | disclosed |