Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 13/20 | 0.67 |
| ▸ | FFAR4 | Q5NUL3 | 9/20 | 0.67 |
| ▸ | THRA | P10827 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 2/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL136463 | 0.86 | RXRA (0.56) | FFAR1FFAR4NR4A2MRGPRX4 | |
| Phenyl Propionic Acid SCHEMBL3127187 | 0.84 | FFAR1 (0.57) | FFAR1FFAR4THRATHRBAKR1B1 | |
| SCHEMBL27821115 | 0.83 | MAOB (0.49) | FFAR1FFAR4NR4A2MRGPRX4 | |
| SCHEMBL23536844 | 0.82 | MAOB (0.61) | FFAR1FFAR4NR4A2 | |
| SCHEMBL5764984 | 0.82 | NR4A2 (0.50) | FFAR1FFAR4NR4A2MRGPRX4 | |
| SCHEMBL27986144 | 0.81 | FFAR1 (0.46) | FFAR1FFAR4NR4A2MRGPRX4 | |
| SCHEMBL27799979 | 0.81 | ALDH1A1 (0.56) | FFAR1FFAR4NR4A2MRGPRX4 | |
| SCHEMBL23536653 | 0.80 | POLB (0.48) | FFAR1FFAR4NR4A2MRGPRX4 | |
| SCHEMBL850085 | 0.80 | MEN1 (0.72) | NR4A2MRGPRX4 | |
| SCHEMBL135927 | 0.80 | NR4A2 (0.49) | FFAR1FFAR4NR4A2MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101952244-B | N,N-disubstituted aminoalkylbiphenyl antagonists of prostaglandin D2 receptors | AMIRA PHARMACEUTICALS INC | 2014-11-05 | — | — | CN | disclosed |
| CN-101952244-A | PGD 2The N of acceptor, N-disubstituted amido alkyl biphenyl antagonist | AMIRA PHARMACEUTICALS INC | 2011-01-19 | — | — | CN | disclosed |