Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.43 |
| ▸ | TSPO | P30536 | 1/20 | 0.42 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1136127 | 0.82 | MRGPRX1 (0.48) | MRGPRX1NPC1RAB9AMAPTHSD17B10 | |
| SCHEMBL28758475 | 0.77 | EPHX2 (0.46) | MRGPRX1MAPTALDH1A1GAAPKM | |
| SCHEMBL1136008 | 0.76 | MRGPRX1 (0.41) | MRGPRX1NPC1RAB9AMAPTHSD17B10 | |
| SCHEMBL1136006 | 0.76 | MRGPRX1 (0.41) | MRGPRX1NPC1RAB9AMAPTHSD17B10 | |
| SCHEMBL27778853 | 0.76 | MRGPRX1 (0.40) | MRGPRX1NPC1RAB9AMAPTHSD17B10 | |
| SCHEMBL27567990 | 0.73 | CYP1A2 (0.49) | MRGPRX1NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL8155806 | 0.73 | LMNA (0.48) | NPC1RAB9AMAPTLMNAGAA | |
| SCHEMBL18914159 | 0.72 | MAPT (0.48) | MAPTHSD17B10ALDH1A1HTTPDE4D | |
| SCHEMBL22897660 | 0.72 | ALDH1A1 (0.56) | NPC1RAB9AMAPTHSD17B10LMNA | |
| SCHEMBL29560833 | 0.72 | ALDH1A1 (0.56) | NPC1RAB9AMAPTHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679392-B | Quinolone compound and pharmaceutical composition | OTSUKA PHARMA CO LTD | 2012-05-30 | — | — | CN | disclosed |
| CN-101679392-A | Quinolone compound and pharmaceutical composition | OTSUKA PHARMA CO LTD | 2010-03-24 | — | — | CN | disclosed |