Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | WNT3A | P56704 | 9/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17681593 | 0.82 | ALDH1A1 (0.56) | EPHX2KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL2088365 | 0.82 | EPHX2 (0.48) | EPHX2KMT2AMRGPRX1MEN1ALDH1A1 | |
| SCHEMBL1275647 | 0.79 | CYP1A2 (0.49) | EPHX2MRGPRX1ALDH1A1MAPTPOLB | |
| SCHEMBL20707771 | 0.77 | KMT2A (0.46) | EPHX2KMT2AMEN1MAPTKDR | |
| SCHEMBL27799953 | 0.77 | MRGPRX1 (0.49) | MRGPRX1ALDH1A1MAPTPKMGAA | |
| SCHEMBL16291113 | 0.73 | GAA (0.54) | EPHX2KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL30663604 | 0.72 | KMT2A (0.55) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| SCHEMBL22173643 | 0.72 | KMT2A (0.55) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| SCHEMBL18579521 | 0.71 | ALDH1A1 (0.56) | WNT3AKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL17101064 | 0.71 | KDR (0.49) | EPHX2ALDH1A1MAPTEGFRFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1738615-A | Diaminotriazoles as inhibitors of protein kinases | VERTEX PHARMA (US) | 2006-02-22 | — | — | CN | disclosed |