Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | MAOA | P21397 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22273595 | 0.85 | MEN1 (0.42) | ALDH1A1KDM4ESMN1; SMN2HPGDMAOA | |
| SCHEMBL24066629 | 0.84 | MEN1 (0.41) | ALDH1A1KDM4ESMN1; SMN2HPGDMAOA | |
| SCHEMBL20240921 | 0.74 | SMN1; SMN2 (0.59) | ALDH1A1KDM4ESMN1; SMN2HPGDMAOA | |
| SCHEMBL2532507 | 0.74 | KDM4E (0.67) | ALDH1A1KDM4ESMN1; SMN2HPGDMAOA | |
| SCHEMBL26423372 | 0.72 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL19887565 | 0.71 | PLA2G2A (0.40) | ALDH1A1KDM4ESMN1; SMN2HPGDMAPT | |
| SCHEMBL31319840 | 0.71 | MAPT (0.43) | ALDH1A1KDM4ESMN1; SMN2HPGDMAOA | |
| SCHEMBL26423373 | 0.70 | ALDH1A1 (0.42) | ALDH1A1KDM4ESMN1; SMN2HPGDHSD17B10 | |
| Xanthone SCHEMBL28171995 | 0.70 | MAOA (0.64) | ALDH1A1KDM4ESMN1; SMN2HPGDMAOA | |
| SCHEMBL13907551 | 0.70 | KMT2A (0.47) | ALDH1A1KDM4ESMN1; SMN2MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101685733-A | High-temperature thermal fuse device | THERM O DISC INC | 2010-03-31 | — | — | CN | disclosed |